Protein Alignment kmr and Plekha4

DIOPT Version :10

• Sequence 1: NP_001097775.2
• Gene: kmr / 5740131
• FlyBaseID: FBgn0085412
• Length: 3090
• Species: Drosophila melanogaster
• Sequence 2: NP_954532.1
• Gene: Plekha4 / 308584
• RGDID: 735133
• Length: 779
• Species: Rattus norvegicus
• Alignment Length: 901
• Identity: 222/901 - (24%)
• Similarity: 332/901 - (36%)
• Gaps: 287/901 - (31%)

  Fly   303 IQQNHPNHVVNQACQTQISAVKPKATPSSEESSSNSTKSPS------HAPLDRKKSAGSIQALKS 361
            ::|..|        ::.:|.....:|.||  .||.|.|.|:      || ..::.:|
  Rat     1 MEQGRP--------RSSLSLTSSASTVSS--LSSLSAKKPTRVVHKVHA-FGKRNNA-------- 46

  Fly   362 PITKRPPSTPVTLSGWLHKQGSDGLKVWRKRWFVLAEYCLYYYKGPEEEKLLGSVLLPSYRVSAC 426
              .:|.|:.||.:.||||||.|.||::|::|||||:.:||:|||...||.:|||||||||.|...
  Rat    47 --LRRDPNLPVHIRGWLHKQDSSGLRLWKRRWFVLSGHCLFYYKDSREESVLGSVLLPSYSVRPD 109

  Fly   427 LPEDKIYRKFAFKCEHQNMRTYWLAADNSEAMMQWVRALAAASLMQA-----------PSSGE-- 478
            .|.....|:|.|..||..||||.||||..|.:..|:|||..||..:.           |..||
  Rat   110 GPGAPRGRRFTFTAEHPGMRTYVLAADTLEDLRGWLRALGKASRAEGEDCGLPRSPARPRPGEGP 174

  Fly   479 ----SEPSVNSSLNHSGENSDS----------GIHTLQSHPGKG---QPTPSSENTGSSGGGSGS 526
                ..|.||.  ...|..|:|          |.|.:.: ||..   ||...|..|.|....|..
  Rat   175 GGPGGPPEVNR--REEGRTSESPEVAPLSRGPGRHEMHA-PGSSADLQPDTWSRRTRSPEPFSPL 236

  Fly   527 GQPLYANAPPKPRR-------INDGGYSSPSPEHNEQQQ--------QHPSRRLMS----PTQQL 572
            .:|....:.|:||.       ::.|..|.|:..|....:        ..|.|:.:|    |.:..
  Rat   237 SRPPSPLSLPRPRSAPVRRPPLSAGDISFPARPHTPLSRIDVRPPLDWGPQRQTLSRPPIPRRGP 301

  Fly   573 YQQQQHQRSQQQQQQQPQQHHAIYDTRTGHVSTALQL------QQA--------------QQQYS 617
            :.:....|..:..|.:..:|.......:...||.|||      .||              .|...
  Rat   302 FSEAGGGRPPRSPQLRTPEHRTQSTQVSSGSSTYLQLPPRPPGTQASMILLPGPPVDSTLHQSLE 366

  Fly   618 LDHL-------EAQFQQQQLDMEEQIARLQQQRAAEEIYGEREMYMAKLMQQRQGPNGTYPTQQQ 675
            .|.|       :...:|.|.|::::....:|..||.|:                       |:||
  Rat   367 TDTLLTKLCGQDRLLRQLQEDLDKRQEEKEQLEAALEL-----------------------TRQQ 408

  Fly   676 LLQAERR---TPDAYGRSK--QQRLFAAAAA----AADYEDIYN-MSQLAGGGGVPMSAQEALL- 729
            |.||.|.   :..|:||.:  |.||....||    ..:.|.::: .|.|....|......|.||
  Rat   409 LGQATREAAASGKAWGRQRLLQDRLVNVRAALCHLTQERERVWDTYSGLEQDLGTLRETLEYLLH 473

  Fly   730 ----QEAASYRRPL---------------SPPSYDGSKHVPAMPQRYTPNHLEASAADQLINTMD 775
                |:.||.::.|               .||..:.....|| |||.     |:|..:.|..:::
  Rat   474 LGSPQDRASAQQQLWMVEDTLAGLGGPQKQPPHTEPKSPSPA-PQRE-----ESSERESLSESLE 532

  Fly   776 LRARTAAAI--VRPHSADFLEYEARAEAAAAAAAAAVAQSQQESGRAPRPKSSLDINRTPDSFYY 838
            |.:..:..:  .:|...|                .|::.||...| :||               .
  Rat   533 LSSPQSPEVDWGQPPGGD----------------RALSSSQSGVG-SPR---------------V 565

  Fly   839 SEASYADKMRKSALYLQSGGAGAAQPQQPGSYRTTGADFNSGVNTIGYENPYERAYKRQELLAEA 903
            |.||..:..::|:..|:: .|..|:|:.                         .|.::.|.:...
  Rat   566 SRASSPECRQQSSPLLRT-KAPLARPRM-------------------------SAQEQLERMRRN 604

  Fly   904 QGGGASSMPRMS--RSASQGRSVASQLQSPQQEDLPPLNVHPGSIFPPSMSTQEIISKNEQFLRS 966
            |..|. |:||.:  |..:.||:::...:.|..|..|                   |....::|||
  Rat   605 QACGL-SLPRPTSPRLLTLGRTLSPVPRQPDMEQRP-------------------IVGAAKWLRS 649

  Fly   967 ASARLPKRSGGMDDDYSAGNSTTTSPTGGAGASNSPQHNLDGERKREESMKRLL-----EWKQRM 1026
                    ||...   |..:|||.||..|            |.|:|..|:.:.|     :|.:.|
  Rat   650 --------SGSWS---SPRHSTTYSPVSG------------GHRERVLSLSQALATEASQWHRLM 691

  Fly  1027 LQSP---LTRKG--IQQGGSNMS-AMSKLGSNPNILLASTAV------ASGARYAP 1070
            ..||   |..:|  :|......| .:.::.|:|....|::|.      .||...||
  Rat   692 TASPERNLDTRGDCLQPSPQPPSEELPQVTSSPTSHKANSATTGFSCQGSGRGLAP 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	55/102 (54%)
Plekha4	NP_954532.1	PH_PEPP1_2_3	49..152	CDD:270068	55/102 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	152..355		42/205 (20%)
		COG4372	381..>487	CDD:443500	32/128 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	495..669		53/280 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	694..766		14/54 (26%)