Protein Alignment kmr and Arhgap22

DIOPT Version :9

• Sequence 1: NP_001097775.2
• Gene: kmr / 5740131
• FlyBaseID: FBgn0085412
• Length: 3090
• Species: Drosophila melanogaster
• Sequence 2: XP_038950392.1
• Gene: Arhgap22 / 306279
• RGDID: 1307237
• Length: 722
• Species: Rattus norvegicus
• Alignment Length: 637
• Identity: 133/637 - (20%)
• Similarity: 214/637 - (33%)
• Gaps: 160/637 - (25%)

  Fly   349 RKKSAGSIQALKSPITKRPPST--PVTLSGWLHKQGSDGLKVWRKRWFVLAEYCLYYYKGPEEEK 411
            |.||....:..:||.....|..  ||..:|||.||.|. :|.|::|||||....|:|||..:|.|
  Rat    19 RSKSLVMGEQSRSPGRPLAPHKLGPVLKAGWLRKQKSI-MKNWQQRWFVLRGDQLFYYKDKDEGK 82

  Fly   412 LLGSVLLPSYRVSACLPEDKIYRKFAFK------CEHQ----NMRTYWLAADNSEAMMQWVRALA 466
            ..|.:.|...:|:..||:.....|..|:      .|.:    |.....|.|.:...|..||:|:
  Rat    83 PQGFISLQGTQVTELLPDPDDPGKHLFEITPGGAAEREKVPANPEALLLMASSQRDMEDWVQAI- 146

  Fly   467 AASLMQAPSSGESEPSVNS------SLNHSGENSDSGIHTLQSHPGKGQPTPSS----------E 515
             ..::.||..|.:..|.::      |....|:..:..:|    |..|..|..:.          .
  Rat   147 -RRVIWAPLGGGTSRSSHAHPVEPLSTGIFGQRLEDTVH----HERKFGPRLAPLLVEQCVDFIR 206

  Fly   516 NTGSSGGGSGSGQPLYANAPPKPRRINDGGYSSPSPEHNEQQQQHPSRRLMSPTQQLYQQQQHQR 580
            ..|.|..|. ...|..||.   .|.:.|.......|..:.....|....|:    :||
  Rat   207 ERGLSEEGL-FRMPGQANL---VRDLQDSFDCGEKPLFDSTTDVHTVASLL----KLY------- 256

  Fly   581 SQQQQQQQPQQHHAIY------------DTRTGHVSTALQLQQ-AQQQYS--------LDHLEAQ 624
              .::..:|....|.|            |...|.|..|.|:.. .|..|:        ||.::|.
  Rat   257 --LRELPEPVIPFARYEDFLSCAQLLTKDEGEGTVELAKQVSNLPQANYNLLRYICRFLDEVQAH 319

  Fly   625 FQQQQLDMEE-------QIARLQQQRAAEEIYG--------------EREMYMAKLMQQRQGPNG 668
            ....::.::.       .|.|.|.:.....:.|              ..:::.....::...|.|
  Rat   320 SDVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHGQLFATPSFEEPASPRG 384

  Fly   669 TYP-----TQQQLLQAERRTPDAYG--RSKQQRLFAAAAAAADYEDIYNMSQLAGGGGV-PMSAQ 725
            |..     ..:::.:..:..|.:.|  ..:...|...|||.........:...||.... |....
  Rat   385 TVQGTVEWGSEEVTRDHQGEPGSSGLPTHRTSSLDGPAAAVLSRTSPPRLGSQAGPAATSPGKRM 449

  Fly   726 EALLQEAASYR----RPLSPPSYDGSKHVPAMPQ---------RYTPNHLEASAADQLINTMDLR 777
            ..|....:|:|    |..||.....|..||.:..         ....:|..||:.|:|.:|...:
  Rat   450 HTLPGWKSSFRQQGSRSESPKGVSSSLEVPIISSGGNWLINGLSSLRSHRRASSGDRLKDTGSAQ 514

  Fly   778 ARTAAAIVRPHSADFLEYEARAEAAAAAAAAAVAQSQQESG-------RA--------------- 820
            ..:....|.|.|      ...:.|:.|:.|.:||.|.:|:.       ||
  Rat   515 RLSTYDNVPPSS------HLSSTASVASTAWSVASSSREASIGSCTACRASNSSACSSLHTEWAL 573

  Fly   821 ---PRPKSSLDINRTPDSFYYSEASYADKMRKSALYLQSGGAGAAQPQQPGS 869
               |.|.|| :.:.:||..:..:.:..             |:|:::|..|||
  Rat   574 EPSPLPSSS-EGHPSPDLGHSLDEACV-------------GSGSSEPNDPGS 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	37/114 (32%)
		PH	372..469	CDD:278594	35/106 (33%)
Arhgap22	XP_038950392.1	PH-like	42..157	CDD:418428	38/117 (32%)
		RhoGAP_ARHGAP22_24_25	173..371	CDD:239855	35/218 (16%)
		SMC_prok_B	<614..>704	CDD:274008

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910