Protein Alignment kmr and Arhgap24

DIOPT Version :9

• Sequence 1: NP_001097775.2
• Gene: kmr / 5740131
• FlyBaseID: FBgn0085412
• Length: 3090
• Species: Drosophila melanogaster
• Sequence 2: XP_038947750.1
• Gene: Arhgap24 / 305156
• RGDID: 1306669
• Length: 815
• Species: Rattus norvegicus
• Alignment Length: 841
• Identity: 165/841 - (19%)
• Similarity: 268/841 - (31%)
• Gaps: 306/841 - (36%)

  Fly   333 ESSSNSTKSPSHAPLDRKKSAGSIQALKSPITKRPPSTPVTLSGWLHKQGSDGLKVWRKRWFVLA 397
            |.:.:||::|        .|.|...|.|              .|||.|||. .:|.|..|||||.
  Rat    69 EENCDSTENP--------HSQGRQNATK--------------CGWLRKQGG-FVKTWHTRWFVLK 110

  Fly   398 EYCLYYYKGPEEEKLLGSVLLPSYRVSACLPEDKIYRKFAFKC----EHQNM----RTYWLAADN 454
            ...|:|:|..:|.|.||::.||..:|......::...||.|:.    |...|    .:|.|.|..
  Rat   111 GDQLHYFKDEDETKPLGTIFLPGNKVIEHPCNEESPGKFLFEVVPGGERDRMTANHESYLLMAST 175

  Fly   455 SEAMMQWVRALAAASLMQAPSSG-----ESEPSVNSSLNHSGENS-----------------DSG 497
            ...|..||:::  ..::..|..|     :.|.:|.....:....:                 :.|
  Rat   176 QNDMEDWVKSI--RRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEG 238

  Fly   498 IHTLQSHPGKGQPTPSSENTGSSGGGSGSGQPLYANAPPKPRRINDGGYSSPSPEHNEQQQQHPS 562
            :..|   ||:                        ||.   .:.:.|.......|..:.....|..
  Rat   239 LFRL---PGQ------------------------ANL---VKELQDAFDCGEKPSFDSNTDVHTV 273

  Fly   563 RRLMSPTQQLYQQQQHQRSQQQQQQQPQQHHAIYDTRTGHVSTALQLQQAQQQYSLDHLEAQFQQ 627
            ..|:    :||         .::..:|...:|.|:   ..:|.|..|.: :::..:..|..|.:.
  Rat   274 ASLL----KLY---------LRELPEPVVPYAKYE---DFLSCATLLSK-EEEAGVKELTKQVKS 321

  Fly   628 QQL---DMEEQIARLQQQRAAEEIYGEREMYMAKLMQQRQGPN--------------GTYPTQQQ 675
            ..:   ::.:.|.|...:  .:...|..:| .|:.:....|||              ||...||.
  Rat   322 LPVVNYNLLKYICRFLDE--VQSYSGVNKM-SAQNLATVFGPNILRPKVEDPLTIMEGTVVVQQL 383

  Fly   676 LLQAERRTPDAYGRSKQQRLFAAAAAAADYEDIYNMSQLAGGGGVPMSAQEALLQEAASYRRPLS 740
            :         :...||..|||     ..|.|              |.|             :|..
  Rat   384 M---------SVMISKHDRLF-----PKDTE--------------PQS-------------KPQE 407

  Fly   741 PP---SYDGSKHVPAMPQRYTPNHLEASAADQLINTMDLRARTAAAIVRPHSADFLEYEARAEAA 802
            .|   :.||.|.|               ...||.|..:  ..|..:.||..|.|..|...|: :.
  Rat   408 GPNSNNNDGHKKV---------------TMGQLQNKEN--NNTKESPVRRCSWDKPESPQRS-SM 454

  Fly   803 AAAAAAAVAQSQQESGRAPRPKSS---LDINRTP-------------------DSFYYSEASYAD 845
            ...:..|::.|:..|     |::|   ||::|:|                   .||..|.|...:
  Rat   455 DNGSPTALSGSKTNS-----PRNSIHKLDVSRSPPLTVKKNPAFNKGSGIVTNGSFSSSNAEGVE 514

  Fly   846 K----------MRKSALYLQSGGAGAAQPQQPGSYR-------TTGADFN--------SGVNTI- 884
            |          .|:::....||........|.|:.|       |.|...|        :|..|:
  Rat   515 KTQTTPNGSLQARRTSSLKSSGTKMGTHSVQNGTVRMGILNTDTLGNSLNGRSMSWLPNGYVTLR 579

  Fly   885 -----------GYEN---PYERAYKRQELL--------AEAQGGGAS---SMPRMSRSASQGRSV 924
                       |..|   .|:..:::..|:        ..|....:|   |:|..|.|.....:.
  Rat   580 DNKQKEPAGESGQHNRLSTYDNVHQQFSLMNLDDKHSVDSATWSTSSCEISLPENSNSCRSSTTT 644

  Fly   925 ASQ------------LQSPQQEDLPPLNVHPGSIFPPSMSTQEIISKNEQFLRSASARLPKRSGG 977
            ..:            |..|.|:||.    |||..            :|:...||...|..:.:..
  Rat   645 CPEQDFYGGNFEDPVLDGPPQDDLS----HPGDY------------ENKSDRRSVGGRSSRATSS 693

  Fly   978 MDDDYSAGNSTTTSPTGGAGASNSPQHNLDGERKREESMKRLLEWKQRMLQSPLTRKGIQQ 1038
            .|      ||.|.  .|...:::|..|:|....| :|..|:.:|::.|:       |.::|
  Rat   694 SD------NSETF--VGNTSSNHSALHSLVSSLK-QEMTKQKIEYESRI-------KSLEQ 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	34/110 (31%)
		PH	372..469	CDD:278594	34/104 (33%)
Arhgap24	XP_038947750.1	PH_RhoGap24	84..197	CDD:241530	37/129 (29%)
		RhoGAP_ARHGAP22_24_25	197..395	CDD:239855	37/256 (14%)
		Smc	<716..>802	CDD:224117	7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910