Protein Alignment kmr and Ppp1r9a

DIOPT Version :9

• Sequence 1: NP_001097775.2
• Gene: kmr / 5740131
• FlyBaseID: FBgn0085412
• Length: 3090
• Species: Drosophila melanogaster
• Sequence 2: XP_006505133.1
• Gene: Ppp1r9a / 243725
• MGIID: 2442401
• Length: 1322
• Species: Mus musculus
• Alignment Length: 1694
• Identity: 301/1694 - (17%)
• Similarity: 560/1694 - (33%)
• Gaps: 582/1694 - (34%)

  Fly  1537 RSTLKKCKKSGTETLKKKTKKRQGKD------------------MPDILKPAKSALALASDSSDA 1583
            :||..|.|..|    ::|||:.:|..                  |...::|:::|..:|......
Mouse    31 KSTFDKPKSDG----EQKTKEGEGSQQSRGRKYGSNVNRIKNLFMQMGMEPSENAAIIAKTRGKG 91

  Fly  1584 DDESSRQQLEAK-----------KLRS--RSRFSLSDTFRPASYYLGASTPLNNYAESSDSEILP 1635
            ...|.:::::.|           ||.|  ..|.|..||.....          :||:.:::.
Mouse    92 RPSSPQRRMKPKEFVEKTDGSVVKLESSVSERISRFDTMHDGP----------SYAKFTETR--- 143

  Fly  1636 PPPIPASPPPMEELKTEEIFSSEHYDTVKRKDSNGKVNLSYEQLPKMHASNTSLN--LPKA-VPS 1697
                     .|.|....|...:..|...|.|....:....:........|:.||:  .|:. ..|
Mouse   144 ---------KMFERSVHESGQNHRYSPKKEKGGGTEPQDEWGGSKSNRGSSDSLDSLSPRTEAVS 199

  Fly  1698 PTLKSSRLSLPDHFTKVRMTPQRLLVPATPPQQHHARTLSDSNYSCQLT-----DTSSRTSSDLD 1757
            ||:  |:||             .:...:.||....:.....::||  :|     :..|.|.::||
Mouse   200 PTV--SQLS-------------AVFENSEPPGALTSGKAESADYS--VTGHYPLNLPSVTVTNLD 247

  Fly  1758 LYRRRGQQQRCTSNNSLPLSSENESVEFRQRSDSELDRQRSRRPLSQESI-SEIESLSEQFE--- 1818
            .:.|...     ||:..|.:.::...|..|:||:....:.:::..|..|: ||...||.:.|
Mouse   248 TFGRLKD-----SNSKPPSNKQDTDTEDAQKSDAVPVPEVAQKGTSLASLPSEESQLSTEAEDVT 307

  Fly  1819 ----ETLSSHELDTYLSHLHLSTGQATPTSHLLN-------DANA--------------AAGADI 1858
                |.|.|.:.|:  .....:..||.|.||:|:       ||.|              ..|.|:
Mouse   308 TAQPEALDSTDKDS--PEEPSAENQAMPKSHILSPRNEPLEDAEANVVGSERAQHQKKDLTGGDL 370

  Fly  1859 LTNLIKPPKTFRNAEDEEQHFYGNIHFLSSTDSIQQL--------GEAGATALRIIHSRNNSNIS 1915
            .:.........|...::...|..:..::.|..::.::        ||.|        :..:....
Mouse   371 TSPDASASSCGREVPEDSNSFESSHVYMHSDYNVYRVRSRYNSDWGETG--------TEQDEEED 427

  Fly  1916 TQSAPYY-----YSELPAPP-----PLNNQRDIHAHGLNIAHIHNPIDRHQFNVDALVDKDQAID 1970
            :....||     |||:...|     |.|.:.......:.:           ||..:..|.|:..|
Mouse   428 SDENNYYQPDMEYSEIVGLPEEEEIPANRKIKFSCAPIKV-----------FNTYSNEDYDRRND 481

  Fly  1971 SKNIYCGQKDNNEKLSNKNLKLNKSVD----LPAEME-------------GSGSSGGALNPVVHS 2018
                     |.:...::...:|.|.|:    .|.|:|             |.|:..|
Mouse   482 ---------DVDPVAASAEYELEKRVEKLELFPVELEKDEDGLGISIIGMGVGADAG-------- 529

  Fly  2019 YLTTTKNTNLARKTIGGSNPSDDGNPNEDGAGENTEEAGKTPSNNVHTNLSVLGGELLWEEDALW 2083
                .:...:..||:     :|.|....||              .:..|..::      |.|.:
Mouse   530 ----LEKLGIFVKTV-----TDGGAAQRDG--------------RIQVNDQIV------EVDGI- 564

  Fly  2084 RESLRRVSQRHARSLDDLDRITAAPPISSTPKAKLSREVTYVNDSLKPRQHPHITNEHDVYVQLM 2148
              ||..|:|..|                :|........|.:|....||.|...:       .||:
Mouse   565 --SLVGVTQNFA----------------ATVLRNTKGNVRFVIGREKPGQVSEV-------AQLI 604

  Fly  2149 DTTSSSHDHDQTDSDVYEVLREETASNLSHKSNELDRETIRQWDAMSSGLMKSNHSGVEATGASS 2213
            ..|.......          ||....:.:....:.|..|:.:...: ||...:|::....||..:
Mouse   605 SQTLEQERRQ----------RELLERHYAQYDADDDENTVAELQGV-SGNCNNNNNRFLKTGEYA 658

  Fly  2214 AHLPLTSSVRSIVQQLNNSSMDDANGNPMATASISVRNVNNLPVGNLTVK----PDPSDVHQESA 2274
                              :..::..|.|:            ||.|::.::    |:..|:
Mouse   659 ------------------TDEEEDEGGPI------------LPSGDVAIEVFELPENEDM----- 688

  Fly  2275 FAPYYGGAAETKYAKNTVLTDRGLYAANGSGLATS-TPQNHQQFRMRHTGSRAEIDMLERETSSQ 2338
            |:|                          |.|.|| .....::.:::|..:.|||        .:
Mouse   689 FSP--------------------------SDLDTSKLSHKFKELQIKHAVTEAEI--------QK 719

  Fly  2339 IRNRLRSAEG------LTRAESIQRLDYLKQHLLDLERHYEKSKPLVNLVDNMVKLGSLYRNDAN 2397
            ::.:|::||.      |.:.:..|.::..|:.:|.||.::.:::.|.:.|:
Mouse   720 LKTKLQAAENEKVRWELEKNQLQQNIEENKERMLKLESYWIEAQTLCHTVN-------------- 770

  Fly  2398 GRVQPATLDRLEFNQRMQEQQMLQEEQQQWERLSP--NQAELQVRELYQ--LDQLLQEESGTLQS 2458
                                :.|:|.|.|::.|..  |:|:..:::..|  ||.:.::|
Mouse   771 --------------------EHLKETQSQYQALEKKYNKAKKLIKDFQQKELDFIKRQE------ 809

  Fly  2459 LQRDK-EDLERA----LGGLRARIHDSNATPMALEAAKKQQHILERELSRVHQLLAENSKKLEQT 2518
            ::|.| |::|:|    :.||:.||.|       |||             .|.:||.:|..::..
Mouse   810 VERKKREEVEKAHLLEVQGLQVRIRD-------LEA-------------EVFRLLKQNGTQVNN- 853

  Fly  2519 VAGNARLEQELLLLRQKVQAVRGSTTNGMN------GDGSHINGDQTAAVLASELERVQSLVGDM 2577
              .|...|:.    ....:..:|.|...:.      .||  ::.|...||  .|.||:.|   ..
Mouse   854 --NNNIFERR----PSPGEVSKGDTMENVEVKQTSCQDG--LSQDLNEAV--PETERLDS---KA 905

  Fly  2578 QRQRHELSSAVRQLTENSTRLYQEIGNKEMNGGGSTNG--SLKKRSNSTSWTETDLDANML---- 2636
            .:.|.:||...|:.....||||..:        .||:|  ||::::...|..|::....:|
Mouse   906 LKTRAQLSVKNRRQRPTRTRLYDSV--------SSTDGEDSLERKAWRVSSPESECGVTLLTPVT 962

  Fly  2637 --RCGSRQQLNDSTLNLSTP-------LYVDT-NSSTKLSDYNR------YNGSSDAIEMSGVDS 2685
              |..|.....:|......|       :..|| :|||..||::.      :..:..|::..  |.
Mouse   963 SPRAFSSHHTTESPGGSQHPEGDPFSSISGDTSSSSTSASDHDTEDSPCCHQATEKALQEK--DD 1025

  Fly  2686 DGF----LDSNPFAL--GLEKQEIKTVRIVKRESERRNRDRSERGLSNSIQNLDQVLEEEQYAQQ 2744
            |.:    ..|:.|.:  |..||:...:....|.:..:.:.|.::              |::.::.
Mouse  1026 DKYPKSLRTSSSFVVQRGKIKQKFADLGAPLRRNPNKGKKRKDK--------------EKEASRF 1076

  Fly  2745 QREQQLYAQNLE----EPMTNGHHS-RSKSLPRNYSEPPKQRHSRHLNGGKQNGHHYNGGYDYDR 2804
            ....:::...||    :|.:....| ||..:|.::....::                 |.|.:
Mouse  1077 SAGSRIFRSKLENWKSKPSSAAQASTRSPCMPFSWFNESRK-----------------GSYSF-- 1122

  Fly  2805 NSNYEHQPPP-PPAPQSNGHHHNHQQREQREHLNPLANAYFAKQLQQQANPSRDSARVALRTKTD 2868
             .|....|.| .|:|::           |........|..|.......:..|.|.:.:....||.
Mouse  1123 -RNLPSAPSPLQPSPET-----------QVSDKTGSKNFTFNDDFSPSSTSSADLSGLGAEPKTP 1175

  Fly  2869 SLQSLNKSLTDISPEPVFQSVAARQIINEMSAGSASEDTEKVVEKV------PPH-HKHRRAVPR 2926
            .|.               ||:|.          |:.|..:.:.:::      |.| ....||
Mouse  1176 GLS---------------QSLAL----------SSDESLDMIDDEILDDGQSPKHTQSQNRA--- 1212

  Fly  2927 EKRRHYTAPNNVNQKAMEKVQAENDMNRNNTNWRARDDLDMEVALRPRMNAPDVVRSALGQ--GE 2989
                       |::.::::|          ::|.....||..|   |..:|..:....|.|  |.
Mouse  1213 -----------VHEWSVQQV----------SHWLMSLSLDQYV---PEFSAQSISGEQLLQLDGN 1253

  Fly  2990 KISENTIDNLLLAPNKIVIPERYIPETLSPEEKKRRQEKVESIKKMLAEAPISSNENESLPPSKI 3054
            |:...   .:..:.::.::.::.....:|.|:.::.|||:|..::.|..     .|.|.:.....
Mouse  1254 KLKAL---GMTSSQDRALVKKKLKEMKMSLEKARKAQEKMEKQREKLRR-----KEQEQMQRKSK 1310

  Fly  3055 NAEK 3058
            .:||
Mouse  1311 KSEK 1314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068
		PH	372..469	CDD:278594
Ppp1r9a	XP_006505133.1	PDZ_5	435..498	CDD:375353	14/82 (17%)
		PDZ	502..593	CDD:214570	23/146 (16%)
		SMC_prok_B	<681..>926	CDD:274008	69/357 (19%)
		SAM_Neurabin-like	1210..1279	CDD:188911	14/98 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2051
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030