DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kmr and grp-1

DIOPT Version :9

Sequence 1:	NP_001097775.2	Gene:	kmr / 5740131	FlyBaseID:	FBgn0085412	Length:	3090	Species:	Drosophila melanogaster
Sequence 2:	NP_498764.1	Gene:	grp-1 / 176140	WormBaseID:	WBGene00001743	Length:	393	Species:	Caenorhabditis elegans

Alignment Length:	125	Identity:	41/125 - (32%)
Similarity:	57/125 - (45%)	Gaps:	35/125 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   376 GWLHKQGSD----GLKVWRKRWFVLAEYCLYYYKGPEEEKLLGSVLLPSY---RVSACLPEDKIY 433
            |||.||.|:    |...|:||||||:|.||||:....:::..|.:.|.:.   :|.|  |.
Worm   266 GWLFKQSSNPLFSGALSWKKRWFVLSENCLYYFDQMTDKEPKGIITLANVGIRKVEA--PS---- 324

  Fly   434 RKFAFK-----------CE-HQNMR-------TYWLAADNSEAMMQWVRALAAASLMQAP 474
            |.|.|:           |: .|:.|       .|.:.|.|.|.|..|:.|:   |.|.||
Worm   325 RPFMFEIFSLSDGQIKACKTEQDGRLVEGRHSIYKICAVNDEDMRSWINAI---SRMMAP 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	37/118 (31%)
kmr	NP_001097775.2	PH	372..469	CDD:278594	37/118 (31%)
grp-1	NP_498764.1	Sec7	60..241	CDD:238100
		PH_GRP1-like	261..382	CDD:269954	41/125 (33%)
		PH	263..380	CDD:278594	39/122 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910