DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kmr and AgaP_AGAP007379

DIOPT Version :9

Sequence 1:	NP_001097775.2	Gene:	kmr / 5740131	FlyBaseID:	FBgn0085412	Length:	3090	Species:	Drosophila melanogaster
Sequence 2:	XP_308452.4	Gene:	AgaP_AGAP007379 / 1269802	VectorBaseID:	AGAP007379	Length:	383	Species:	Anopheles gambiae

Alignment Length:	217	Identity:	51/217 - (23%)
Similarity:	81/217 - (37%)	Gaps:	66/217 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 NDLQTPGSEHGT---VYIQQNHPNHVVNQ-----AC----QTQISAVKPKATPSSEESSSNSTKS 341
            |.||....:.||   :|:..:.| .|:|.     .|    :.||      |.||:.||.
Mosquito   192 NSLQLTFMKEGTTRHIYVYHDDP-EVINNWYMAIRCAKLHRLQI------AYPSASESD------ 243

  Fly   342 PSHAPLDRKKSAGSIQALKSPITKRPPSTPVTLSGWLHKQGSDGLKVWRKRWFVLAEYCLYYYKG 406
                         .:..|....|:         .|||.|.|......:::|||.|.:..|.|:..
Mosquito   244 -------------LVDLLTHDFTR---------EGWLLKTGPRATDSYKRRWFTLDDRKLMYHDD 286

  Fly   407 -----PEEEKLLGSVLLPSYRVSACLP---EDKIYRKFAFKCEHQNMRTYWLAADNSEAMMQWVR 463
                 |:.|..||: .|..|.|....|   :|:.|....|..|    |.|.:::.:.:...:|:.
Mosquito   287 QLDAHPKGEIFLGN-QLDGYSVRIGAPPGAKDQGYSFTLFTPE----RVYNMSSHSEQDRDEWIA 346

  Fly   464 ALAAASLMQAPSSGESEPSVNS 485
            |:  .::::.|.|    |..||
Mosquito   347 AI--QNVLERPLS----PQDNS 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kmr	NP_001097775.2	PH_PEPP1_2_3	366..469	CDD:270068	27/110 (25%)
kmr	NP_001097775.2	PH	372..469	CDD:278594	27/104 (26%)
AgaP_AGAP007379	XP_308452.4	ArfGap	6..123	CDD:279720
		PH1_ADAP	130..237	CDD:270072	13/51 (25%)
		PH	132..225	CDD:278594	9/33 (27%)
		PH2_ADAP	251..354	CDD:241282	28/118 (24%)
		PH	253..353	CDD:278594	28/115 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910