DRSC/TRiP Functional Genomics Resources

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Protein Alignment kmr and gab2

DIOPT Version :9

Sequence 1:NP_001097775.2 Gene:kmr / 5740131 FlyBaseID:FBgn0085412 Length:3090 Species:Drosophila melanogaster
Sequence 2:XP_002936593.1 Gene:gab2 / 100498316 XenbaseID:XB-GENE-494700 Length:679 Species:Xenopus tropicalis


Alignment Length:719 Identity:149/719 - (20%)
Similarity:238/719 - (33%) Gaps:206/719 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   372 VTLSGWLHKQGSD-GLK--VWRKRWFVLAE-------YCLYYYKGPEEEKLLGSVLLPSYRVSAC 426
            |...|||.|...: .|:  .|:||||:|..       ..|.|||....:|.:..:     .:|.|
 Frog     6 VVYCGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHAKKPIRVI-----NLSCC 65

  Fly   427 LPED--------KIYRKFAFKCEHQNMRTYWLAADNSEAMMQWVRALAAASLMQAPSSGESEPSV 483
            ...|        ::...:.|..: .|.||::|.|:..|.|.:|||::...               
 Frog    66 EQVDAGLTFNKKELQDSYIFDIK-TNDRTFYLVAETEEEMNKWVRSICQI--------------- 114

  Fly   484 NSSLNHSGENSDS--GIHTLQSHPGKGQPTPSSENTGS--------SGGGSGSGQPLYANAPPKP 538
             ...|.|.||.||  .|.:|:..|   :.:|:..|..|        :...|.|.||.........
 Frog   115 -CGFNQSEENGDSLRNIQSLRHGP---RSSPAEFNNSSHHLLRERKTSAPSHSSQPTLFTFESPS 175

  Fly   539 RRINDGGYSSPSPE-----HNEQQQQHPSRRLMSPTQQLYQQQQHQRSQQQQQQQPQQHHAIYDT 598
            ...:....|:.:|:     |....|:..:.|..| ..|..:.....||....|:..|.:      
 Frog   176 NHAHQTALSTSAPQDYLFLHQCMSQKSETMRSAS-FSQATRSSFFMRSDSAVQKLVQGY------ 233

  Fly   599 RTGHVSTALQLQQAQQQYSL---DHLEAQFQQQQLDM----------EEQIARLQQQRAAEEIYG 650
              ||....:. .|....|||   ..|.::.:....|:          :..:..|:.:  :|::|.
 Frog   234 --GHCLNGIS-GQVHGFYSLPKPSRLSSELRDSAYDLPRSFGSDTPTKSSLTGLESE--SEDVYC 293

  Fly   651 EREMYMAKLMQQRQGPNGTYPTQQQLLQAERRTPDAYGRSKQQRLFAAAAAAADY---------- 705
            .:....|...:.|:....:|......|.. .:.|..:...|...  |...|:.|:          
 Frog   294 YKTPSNALCKELRELSTDSYDIPGTPLSV-YQIPRTFTLDKNHN--ALGLASNDFHSTPPPRPPK 355

  Fly   706 ----EDIYNMSQLA---GGGGVPMSAQEALLQEAASYRRPLSPPSYDGSKHVPAMPQRYTPNHLE 763
                |.|:...|..   .|..|.|          .:..|..:.|:.:..:|..:..:.|....|.
 Frog   356 PGQAETIWGSPQPQHHHNGDNVAM----------VNLPRRNTLPAVENKRHRASSVEAYDYPQLG 410

  Fly   764 ASAADQLINTM----DLRARTAAAIVRPHSADFLEYEARAEAAAAAAAAAVAQSQQESGRAP-RP 823
            ..:.||.:.::    :...:|.:::||..|||                       .|....| .|
 Frog   411 DFSTDQSVESVHDGFNSYLQTKSSLVRSDSAD-----------------------SEDNYVPMNP 452

  Fly   824 KSSLDINRTPDSFYYSEASYADKMRKSALYLQSGGAGAAQPQQPGSYRTTGADFNSGVNTIGYEN 888
            .||...|             .:|:..:|   ||    |..|..||..:.....|:|  ||     
 Frog   453 GSSSQFN-------------IEKLNDNA---QS----AYLPMSPGPNQFDFLGFSS--NT----- 490

  Fly   889 PYERAYKRQELLAEAQGGGASSMPRMSR-SASQGRSVASQLQSPQQEDLPPLNVHPGSIF----- 947
                       |...:|..||..||.|| |..|...|...|:..::....||::...:|.     
 Frog   491 -----------LPARKGSTASLCPRPSRVSDIQPPPVNRNLKPDRKSKPTPLDLRGSAIIDELPF 544

  Fly   948 -----------PPSMSTQEIISKNEQFLRSASAR--LPKRSGGMDDDYSA-GNSTTTSPTGGAGA 998
                       |.||.     |.:.|..|..||:  ....||..:::|.| .|..:.||  |...
 Frog   545 KSPVTRSWSRPPHSMK-----SSSSQCCRPVSAQSITSTSSGDSEENYVAMQNPVSASP--GTSG 602

  Fly   999 SNSP 1002
            :|||
 Frog   603 TNSP 606

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kmrNP_001097775.2 PH_PEPP1_2_3 366..469 CDD:270068 31/114 (27%)
PH 372..469 CDD:278594 31/114 (27%)
gab2XP_002936593.1 PH-like 3..125 CDD:388408 35/140 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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