Protein Alignment Pp1-Y1 and PPP4C

DIOPT Version :10

• Sequence 1: NP_001104152.3
• Gene: Pp1-Y1 / 5740113
• FlyBaseID: FBgn0261399
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_002711.1
• Gene: PPP4C / 5531
• HGNCID: 9319
• Length: 307
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 129/287 - (44%)
• Similarity: 181/287 - (63%)
• Gaps: 7/287 - (2%)

  Fly    17 LDEMIASLLSWKIDRKMMVPESDIIKLLKQARQVLMSEPMLLTVEAPVNVLGDIHGQYNDLLRYF 81
            ||..|..|     .|..::.||::..|..:||::|:.|..:..|::||.|.||||||:.||...|
Human     7 LDRQIEQL-----RRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELF 66

  Fly    82 ETSGHPPKKRYLMLGDYVDRGKYSVETLTLLLAYKVRYPTSIHLLRGNHESAAINRYYGFYDECK 146
            ...|..|:..||.:||:||||.|||||..||||.|||||..|.|:||||||..|.:.|||||||.
Human    67 RVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECL 131

  Fly   147 RRF-TIRLWRMFVDCYDCLPVAAIINSKIFCCHGGLSPSLHNLNDIQHLQRPAEVDRNGLLCDLL 210
            |:: ::.:||...:.:|.|.::|||:.||||.|||||||:..|:.|:.:.|..||..:|.:||||
Human   132 RKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLL 196

  Fly   211 WSDPDPTAIGWEKNSRGVSFTFGVDIVETFLSRFSFDLICRAHQVVEDGYEFFAKRQLITVFSAV 275
            ||||:.|. ||..:.||..:.||.|:|..|.:....|:||||||:|.:||::.....::||:||.
Human   197 WSDPEDTT-GWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAP 260

  Fly   276 NYCGEFDNAGAMMCVDAELNITLVVMK 302
            |||....|..|::.:|..|....::.:
Human   261 NYCYRCGNVAAILELDEHLQKDFIIFE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y1	NP_001104152.3	MPP_superfamily	17..303	CDD:472684	129/287 (45%)
PPP4C	NP_002711.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	129/287 (45%)