Protein Alignment Pp1-Y1 and PPP2CB

DIOPT Version :10

• Sequence 1: NP_001104152.3
• Gene: Pp1-Y1 / 5740113
• FlyBaseID: FBgn0261399
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001009552.1
• Gene: PPP2CB / 5516
• HGNCID: 9300
• Length: 309
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 133/295 - (45%)
• Similarity: 180/295 - (61%)
• Gaps: 7/295 - (2%)

  Fly    13 FEKYLDEMIASLLSWKIDRKMMVPESDIIKLLKQARQVLMSEPMLLTVEAPVNVLGDIHGQYNDL 77
            |.|.||:.:..|...|     .:.|:.:..|.::|:::|..|..:..|..||.|.||:|||::||
Human     6 FTKELDQWVEQLNECK-----QLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDL 65

  Fly    78 LRYFETSGHPPKKRYLMLGDYVDRGKYSVETLTLLLAYKVRYPTSIHLLRGNHESAAINRYYGFY 142
            :..|...|..|...||.:|||||||.|||||:|||:|.|||||..|.:|||||||..|.:.||||
Human    66 MELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFY 130

  Fly   143 DECKRRF-TIRLWRMFVDCYDCLPVAAIINSKIFCCHGGLSPSLHNLNDIQHLQRPAEVDRNGLL 206
            |||.|:: ...:|:.|.|.:|.||:.|:::.:|||.|||||||:..|:.|:.|.|..||...|.:
Human   131 DECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPM 195

  Fly   207 CDLLWSDPDPTAIGWEKNSRGVSFTFGVDIVETFLSRFSFDLICRAHQVVEDGYEFFAKRQLITV 271
            |||||||||... ||..:.||..:|||.||.|||.......|:.||||:|.:||.:...|.::|:
Human   196 CDLLWSDPDDRG-GWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTI 259

  Fly   272 FSAVNYCGEFDNAGAMMCVDAELNITLVVMKPKKR 306
            |||.|||....|..|:|.:|..|..:.:...|..|
Human   260 FSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y1	NP_001104152.3	MPP_superfamily	17..303	CDD:472684	129/286 (45%)
PPP2CB	NP_001009552.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	130/289 (45%)