Protein Alignment Pp1-Y1 and PPP2CA

DIOPT Version :10

• Sequence 1: NP_001104152.3
• Gene: Pp1-Y1 / 5740113
• FlyBaseID: FBgn0261399
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_002706.1
• Gene: PPP2CA / 5515
• HGNCID: 9299
• Length: 309
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 134/297 - (45%)
• Similarity: 181/297 - (60%)
• Gaps: 7/297 - (2%)

  Fly    11 QMFEKYLDEMIASLLSWKIDRKMMVPESDIIKLLKQARQVLMSEPMLLTVEAPVNVLGDIHGQYN 75
            ::|.|.||:.|..|...|     .:.||.:..|.::|:::|..|..:..|..||.|.||:|||::
Human     4 KVFTKELDQWIEQLNECK-----QLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFH 63

  Fly    76 DLLRYFETSGHPPKKRYLMLGDYVDRGKYSVETLTLLLAYKVRYPTSIHLLRGNHESAAINRYYG 140
            ||:..|...|..|...||.:|||||||.|||||:|||:|.||||...|.:|||||||..|.:.||
Human    64 DLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG 128

  Fly   141 FYDECKRRF-TIRLWRMFVDCYDCLPVAAIINSKIFCCHGGLSPSLHNLNDIQHLQRPAEVDRNG 204
            |||||.|:: ...:|:.|.|.:|.||:.|:::.:|||.|||||||:..|:.|:.|.|..||...|
Human   129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEG 193

  Fly   205 LLCDLLWSDPDPTAIGWEKNSRGVSFTFGVDIVETFLSRFSFDLICRAHQVVEDGYEFFAKRQLI 269
            .:|||||||||... ||..:.||..:|||.||.|||.......|:.||||:|.:||.:...|.::
Human   194 PMCDLLWSDPDDRG-GWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVV 257

  Fly   270 TVFSAVNYCGEFDNAGAMMCVDAELNITLVVMKPKKR 306
            |:|||.|||....|..|:|.:|..|..:.:...|..|
Human   258 TIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y1	NP_001104152.3	MPP_superfamily	17..303	CDD:472684	130/286 (45%)
PPP2CA	NP_002706.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	131/289 (45%)