DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pp1-Y1 and ppp1cb

DIOPT Version :9

Sequence 1:	NP_001104152.3	Gene:	Pp1-Y1 / 5740113	FlyBaseID:	FBgn0261399	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001011467.1	Gene:	ppp1cb / 496958	XenbaseID:	XB-GENE-961670	Length:	327	Species:	Xenopus tropicalis

Alignment Length:	298	Identity:	176/298 - (59%)
Similarity:	224/298 - (75%)	Gaps:	3/298 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EKYLDEMIASLLSWKIDRK---MMVPESDIIKLLKQARQVLMSEPMLLTVEAPVNVLGDIHGQYN 75
            |..:|.:|:.||..:..|.   :.:.|:::..|..::|::.:|:|:||.:|||:.:.|||||||.
Frog     5 ELNVDSLISRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYT 69

  Fly    76 DLLRYFETSGHPPKKRYLMLGDYVDRGKYSVETLTLLLAYKVRYPTSIHLLRGNHESAAINRYYG 140
            ||||.||..|.||:..||.|||||||||.|:||:.||||||::||.:..|||||||.|:|||.||
Frog    70 DLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYG 134

  Fly   141 FYDECKRRFTIRLWRMFVDCYDCLPVAAIINSKIFCCHGGLSPSLHNLNDIQHLQRPAEVDRNGL 205
            |||||||||.|:||:.|.||::|||:|||::.|||||||||||.|.::..|:.:.||.:|...||
Frog   135 FYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGL 199

  Fly   206 LCDLLWSDPDPTAIGWEKNSRGVSFTFGVDIVETFLSRFSFDLICRAHQVVEDGYEFFAKRQLIT 270
            ||||||||||....||.:|.||||||||.|:|..||:|...||||||||||||||||||||||:|
Frog   200 LCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVT 264

  Fly   271 VFSAVNYCGEFDNAGAMMCVDAELNITLVVMKPKKRIA 308
            :|||.||||||||||.||.||..|..:..::||.::.|
Frog   265 LFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKA 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-Y1	NP_001104152.3	MPP_superfamily	17..303	CDD:301300	172/288 (60%)
Pp1-Y1	NP_001104152.3	PP2Ac	36..305	CDD:197547	169/268 (63%)
ppp1cb	NP_001011467.1	MPP_PP1_PPKL	7..297	CDD:277359	172/289 (60%)
ppp1cb	NP_001011467.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..327
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930