back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PTGIS and Cyp28a5

DIOPT Version :9

Sequence 1:	NP_000952.1	Gene:	PTGIS / 5740	HGNCID:	9603	Length:	500	Species:	Homo sapiens
Sequence 2:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	232	Identity:	62/232 - (26%)
Similarity:	107/232 - (46%)	Gaps:	35/232 - (15%)

- Green bases have known domain annotations that are detailed below.

Human   244 ARLA--RRAHRSKWLESYLLHLEEMGVSEEMQARA----LVLQLWATQGNMGPAAFWLLLFLLKN 302
            |:||  ::..||.:|: |:|.|.|....:..|..|    .:|..:.|...:   ...:||.|.:|
  Fly   266 AQLAAGKQFERSDFLD-YILQLGEKRNLDNRQLLAYSMTFLLDGFETTATV---LAHILLNLGRN 326

Human   303 PEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITREVVVD-LA 366
            .||...:|.|:.|.|        |..|:..:.|...|.||:.:.|::||....|::.::..: :.
  Fly   327 KEAQNLLREEIRSHL--------QDGTIAFEKLSDLPYLDACVQETIRLFPPGFMSNKLCTESIE 383

Human   367 MPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYN 431
            :|..:|..|.:.:|..::: |......|.|.:.:|:.|:..|||.||.:  |.|     |.:...
  Fly   384 IPNKEGPNFVVEKGTTVVV-PHYCFMLDEEFFPNPQSFQPERFLEPDAA--KTF-----RERGVF 440

Human   432 MPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELIN 468
            |.:|.|...|:|..:|...||..:        :|||:
  Fly   441 MGFGDGPRVCIGMRFATVQIKAAI--------VELIS 469

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.