DRSC/TRiP Functional Genomics Resources

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Protein Alignment PTGIR and ser-5

DIOPT Version :9

Sequence 1:NP_000951.1 Gene:PTGIR / 5739 HGNCID:9602 Length:386 Species:Homo sapiens
Sequence 2:NP_492273.2 Gene:ser-5 / 184572 WormBaseID:WBGene00008890 Length:454 Species:Caenorhabditis elegans


Alignment Length:364 Identity:79/364 - (21%)
Similarity:132/364 - (36%) Gaps:93/364 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    17 PATSTLMFVAGVV-------GNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSP--AVF 72
            ||...|:.:..|:       ||.|.|  ....|..|.:. .:||..|..||.|....:.|  ||:
 Worm    59 PAVLVLLCIPAVIIILLTIFGNLLVL--FFKARVGRTNT-TLLVWNLGLTDFLVGVIVLPMGAVY 120

Human    73 VAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCAR 137
            :.|.:...       |..||..:..|...|...|::.:..::|:|.||::.|..|..:    ..:
 Worm   121 LIYRKWIF-------GRFLCRLWVAADVTFCTCSVVTICVISVDRYLAVTRPLRYKSI----VTK 174

Human   138 LALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAG-----LVALLVA 197
            ..:.::.....:|.:..||               ..:||.||.....||.:.|     |...:|.
 Worm   175 TKVISVMTIIWIFSSSILL---------------TTVRWEQPECYDDSLCFVGNEIRHLAHSVVF 224

Human   198 AIFLCNGSVTLSL-CRMYRQQKRHQGSLGP-----------------------RPRTGEDE--VD 236
            |.|| ..||||:| .|:|:..:..|.:|..                       |...|:..  |:
 Worm   225 AFFL-PASVTLTLYWRIYKLARNRQKALDRGFLMILGSNMNFLTNTLSQQTTLRVHFGKTNGMVE 288

Human   237 H--LIL---------LALMTVVMAVCSLPL------TIRCFTQAVAPDSSSEMGDLLAFRFYAFN 284
            |  .:|         |.:::.....|.||.      ..:|  ....|..:.::...|.:.....|
 Worm   289 HQRRVLRTHERIAKTLGVVSCSFLFCWLPFFGLYLTNYKC--SGCVPPIAIDVASWLGYCNSMLN 351

Human   285 PILDPWVFILFRKAVFQR-LKLWVC---CLCLGPAHGDS 319
            ||:..:....|:::.|:. :.:|..   ||...||..|:
 Worm   352 PIIYSFTVKEFKRSAFRLVVPIWQFVNRCLPFVPAPPDN 390

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PTGIRNP_000951.1 7tm_GPCRs 14..304 CDD:333717 73/344 (21%)
TM helix 1 16..40 CDD:320095 8/29 (28%)
TM helix 2 50..72 CDD:320095 8/23 (35%)
TM helix 3 93..115 CDD:320095 3/21 (14%)
TM helix 4 138..154 CDD:320095 1/15 (7%)
TM helix 5 181..204 CDD:320095 8/27 (30%)
TM helix 6 235..260 CDD:320095 7/41 (17%)
TM helix 7 271..296 CDD:320095 4/24 (17%)
ser-5NP_492273.2 7tmA_amine_R-like 64..365 CDD:320098 70/332 (21%)
TM helix 1 65..87 CDD:320098 5/23 (22%)
TM helix 2 96..118 CDD:320098 7/21 (33%)
TM helix 3 134..156 CDD:320098 3/21 (14%)
TM helix 4 179..195 CDD:320098 3/30 (10%)
TM helix 5 215..238 CDD:320098 10/23 (43%)
TM helix 6 298..323 CDD:320098 4/24 (17%)
TM helix 7 334..359 CDD:320098 4/24 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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