DRSC/TRiP Functional Genomics Resources

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Protein Alignment PTGIR and octr-1

DIOPT Version :9

Sequence 1:NP_000951.1 Gene:PTGIR / 5739 HGNCID:9602 Length:386 Species:Homo sapiens
Sequence 2:NP_001024569.1 Gene:octr-1 / 184469 WormBaseID:WBGene00006411 Length:408 Species:Caenorhabditis elegans


Alignment Length:264 Identity:54/264 - (20%)
Similarity:99/264 - (37%) Gaps:51/264 - (19%)


- Green bases have known domain annotations that are detailed below.


Human     4 SCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLS 68
            :|.||.....::....:.::.:  :.||.|.:..:...|..|......|:..||..|:|....:.
 Worm    14 ACLNLGEAVLTISSMLTVMLLI--IFGNLLVVVTVYRDRKLRMQRQNWLIVSLAVADMLVGLLVM 76

Human    69 PAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGP 133
            | :.:.|    .::|....|..||:.:......|..||:|.:.|::::|..:::.|..|.....|
 Worm    77 P-LTLTY----EIVGEWTMGNILCEIWLALDVLFVTASILHICAISLDRYFSVTSPLTYPATRTP 136

Human   134 RCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFS-----LAYAGLVA 193
            ....:.:...:...:|.|..|:.|           |   |...|: |..:.|     :.|:.|.:
 Worm   137 LRMFIYIGVSWIVSLLICLPPIFG-----------W---RPERAE-GECSVSTDLGYVLYSSLGS 186

Human   194 LLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDE-VDHLILLALMTVVMAVCSLPLTI 257
            ..:..:.|     .:...::|....||.     |.|..|.| .||.:.:             |||
 Worm   187 FYIPVVIL-----IIVYAKIYSITIRHS-----RQRLKETERRDHTLNM-------------LTI 228

Human   258 RCFT 261
            |..|
 Worm   229 RSST 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PTGIRNP_000951.1 7tm_GPCRs 14..304 CDD:333717 51/254 (20%)
TM helix 1 16..40 CDD:320095 3/23 (13%)
TM helix 2 50..72 CDD:320095 6/21 (29%)
TM helix 3 93..115 CDD:320095 5/21 (24%)
TM helix 4 138..154 CDD:320095 2/15 (13%)
TM helix 5 181..204 CDD:320095 4/27 (15%)
TM helix 6 235..260 CDD:320095 6/24 (25%)
TM helix 7 271..296 CDD:320095
octr-1NP_001024569.1 7tmA_alpha2_AR 22..389 CDD:320187 51/256 (20%)
TM helix 1 24..48 CDD:320187 3/25 (12%)
TM helix 2 58..80 CDD:320187 6/22 (27%)
TM helix 3 96..118 CDD:320187 5/21 (24%)
TM helix 4 141..157 CDD:320187 2/15 (13%)
TM helix 5 176..199 CDD:320187 3/27 (11%)
TM helix 6 322..347 CDD:320187
TM helix 7 357..382 CDD:320187
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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