DRSC/TRiP Functional Genomics Resources

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Protein Alignment PTGFR and srx-21

DIOPT Version :9

Sequence 1:NP_000950.1 Gene:PTGFR / 5737 HGNCID:9600 Length:359 Species:Homo sapiens
Sequence 2:NP_503291.3 Gene:srx-21 / 185166 WormBaseID:WBGene00005912 Length:294 Species:Caenorhabditis elegans


Alignment Length:296 Identity:60/296 - (20%)
Similarity:110/296 - (37%) Gaps:46/296 - (15%)


- Green bases have known domain annotations that are detailed below.


Human    29 SVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYA 93
            |:.|.:  ||.|:::|..|:.|..|     .....:||.::.....|.:....|:     ...|.
 Worm     9 SITFMI--MTGGVMANVYALIIAGK-----MSSMNSSFGIITKNQEICNLLMCLL-----FLFYV 61

Human    94 SDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSG 158
            ...:...|:.........|:..:......:.|..::|..|...|..|..:....|:.:.|.|::.
 Worm    62 CPMQLTDFEPFVKFSKYIGLAAMIIYEASMNLHLIIACNRLFAVFLPFHYDQLFTNYNTKFMVAF 126

Human   159 VCLFAVFIALL--PILGHRDYKIQASRTWCFYNTEDIK--DWEDRFYL--------LLFSFLGLL 211
            ..|..:||..|  .|||...:....|.|:.|..|....  .|...|.|        |:|:.|...
 Worm   127 SWLIGLFICTLFYFILGCHFFYSDTSFTFGFRETRRCTKITWYSDFMLNNSLVMVTLVFNLLTAY 191

Human   212 ALGV---SLLCNAITGIT--LLRVK--FKSQQHRQGRS-------HHL-------EMVIQLLAIM 255
            ..|.   |:|..|.:.::  |.|.:  |..|...||.|       ::|       ::::.|||.:
 Worm   192 KAGTTSRSMLQAAGSSMSKQLKRRERNFLRQSFFQGLSMFAGQLTYYLTAPLVDSKIIVFLLASL 256

Human   256 CVSCICWSPFLVTMANIGIN-GNHSLETCETTLFAL 290
            ......:...::.:.|..:. ..|:.:...|::|.:
 Worm   257 WAFVHAFEGGIILLTNKDVRIAAHTKKLSVTSVFVI 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PTGFRNP_000950.1 7tmA_FP 27..316 CDD:320273 60/296 (20%)
TM helix 1 28..54 CDD:320273 8/24 (33%)
TM helix 2 66..92 CDD:320273 3/25 (12%)
TM helix 3 108..138 CDD:320273 4/29 (14%)
TM helix 4 150..172 CDD:320273 6/23 (26%)
TM helix 5 197..226 CDD:320273 9/39 (23%)
TM helix 6 242..272 CDD:320273 5/43 (12%)
TM helix 7 283..308 CDD:320273 2/8 (25%)
srx-21NP_503291.3 TM helix 1 8..32 CDD:341315 9/29 (31%)
7TM_GPCR_Srx 12..272 CDD:370981 55/271 (20%)
TM helix 2 39..65 CDD:341315 4/30 (13%)
TM helix 3 77..106 CDD:341315 4/28 (14%)
TM helix 4 119..138 CDD:341315 5/18 (28%)
TM helix 5 164..188 CDD:341315 5/23 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D412827at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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