Protein Alignment JPH3 and jph3

DIOPT Version :10

• Sequence 1: NP_065706.2
• Gene: JPH3 / 57338
• HGNCID: 14203
• Length: 748
• Species: Homo sapiens
• Sequence 2: XP_017949016.1
• Gene: jph3 / 105947054
• XenbaseID: XB-GENE-987974
• Length: 755
• Species: Xenopus tropicalis
• Alignment Length: 761
• Identity: 602/761 - (79%)
• Similarity: 654/761 - (85%)
• Gaps: 19/761 - (2%)

Human     1 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTW 65
            |||||||||||||||||||:||||||||:||||||||||.|||||||||||||||||||||||||
 Frog     1 MSSGGRFNFDDGGSYCGGWQDGKAHGHGICTGPKGQGEYAGSWSHGFEVLGVYTWPSGNTYQGTW 65

Human    66 AQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTY 130
            |||||||:|:||||||||:||||||||||||||||.|||||||||||||||||||||||||||||
 Frog    66 AQGKRHGLGVESKGKWVYRGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTY 130

Human   131 QGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDASPAVAGSPAVSRGG 195
            ||||..|:|.||||||||||||||||||||||||||||||||||||||||||..|:|||||||||
 Frog   131 QGQWAAGIRHGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDASCTVSGSPAVSRGG 195

Human   196 FVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDI 260
            |||:||||:||||:||||:||||:|||||||||||||||||||||||||||||||||||||||||
 Frog   196 FVLMAHSDAEILKNKKKGIFRRSILSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDI 260

Human   261 HSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGC 325
            :|||||||.|.||:||||||||||||.|:||||:||||||||||||||||||||||:|:||||||
 Frog   261 NSTISLGEGETELSVIEDDIDATTTEVYMGEWKHDKRSGFGVSQRSDGLKYEGEWANNKRHGYGC 325

Human   326 MTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSH 390
            ||||||||||||||.|:||.||||||||||||||||||||||:.|||...|||||||||||||||
 Frog   326 MTFPDGTKEEGKYKHNVLVSGKRKNLIPLRASKIREKVDRAVDEAERVCNIAKQKAEIAASRTSH 390

Human   391 SRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQTSCDDIEVLSTGTPLQQ 455
            |||||:||.|||.||||||:||||:|||||||||||||||:.||||.|.|.|||||:||.||.|.
 Frog   391 SRAKADAAATAALKAQEEAQIARISAKEFSPSFQHRENGLKCQRPKHQNSSDDIEVISTETPPQH 455

Human   456 ESPELYRKGTTPSDLTPDDSPLQSFPTSPAATPP---PAPAARNKVAHFSRQVSVDEERGGDIQM 517
            :||||||||||| |:||||||::|...||.:|||   |.|.:|||.||||||:||||:|||||||
 Frog   456 DSPELYRKGTTP-DVTPDDSPMRSPLCSPPSTPPPTQPVPKSRNKSAHFSRQLSVDEDRGGDIQM 519

Human   518 LLEGRAGDCAR-SSWGEEQAGGSR-GVRSGALRGGLLV-DDFRTRGSGRKQ-PGNPKPRERRTES 578
            |||||.||.|| :||.|  .||.| |:..|...|...: :|...:.:|.|. ..|.|||||..:|
 Frog   520 LLEGRGGDYARPNSWSE--VGGGRIGMSQGNPLGPCSIPEDLLLKSTGHKHVVSNHKPRERWADS 582

Human   579 PPVFTWTSHHRASNHSPGGSRLLELQEEKLSNYRMEMKPLLRM-----ETHPQKRRYSKGGACRG 638
            |...:||| ||..||||.|::|||:.|||||||.||||||.||     |.|.|||::||.|. |.
 Frog   583 PTTISWTS-HRTHNHSPSGNKLLEVDEEKLSNYEMEMKPLKRMDSYMQEVHTQKRQFSKAGP-RN 645

Human   639 LGDDHRPEDRGFGVQRLRSKAQNKENFRPASSAEPAVQKLASLRLG-GAEPRLLRWDLTFSPPQK 702
            ..:.|..|||.:||||||||.|||||.|||:||||.||||.:||.| ..|.||||.|||.|||||
 Frog   646 TPETHHLEDRMYGVQRLRSKPQNKENLRPATSAEPTVQKLDTLRFGEKGESRLLRRDLTLSPPQK 710

Human   703 SLPVALESDEENGDELKSSTGSAPILVVMVILLNIGVAILFINFFI 748
            ||||||:|||||..||| ||||||||||||||||||||||||:|||
 Frog   711 SLPVALDSDEENSAELK-STGSAPILVVMVILLNIGVAILFIHFFI 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JPH3	NP_065706.2	COG4642	<3..144	CDD:443680	129/140 (92%)
		MORN 1	15..37		19/21 (90%)
		MORN 2	39..60		19/20 (95%)
		MORN 3	61..82		18/20 (90%)
		MORN 4	83..105		19/21 (90%)
		MORN 5	107..129		21/21 (100%)
		MORN 6	130..152		17/21 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	230..259		28/28 (100%)
		PLN03185	287..>345	CDD:215619	50/57 (88%)
		MORN 7	288..310		19/21 (90%)
		MORN 8	311..333		19/21 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	416..496		57/82 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..597		31/74 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	624..649		11/24 (46%)
jph3	XP_017949016.1	COG4642	<3..144	CDD:443680	129/140 (92%)
		PLN03185	103..>332	CDD:215619	207/228 (91%)
		MORN	311..333	CDD:308220	19/21 (90%)