Protein Alignment PTGER2 and npr-5

DIOPT Version :9

• Sequence 1: NP_000947.2
• Gene: PTGER2 / 5732
• HGNCID: 9594
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_001024265.1
• Gene: npr-5 / 190386
• WormBaseID: WBGene00021983
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 316
• Identity: 72/316 - (22%)
• Similarity: 133/316 - (42%)
• Gaps: 65/316 - (20%)

Human    31 MFSAGVLGNLIALALLARRWRGDVGCSAGRRSSL-SLFHVLVTELVFTDLLGTCLISPV-----V 89
            :|..|:.||            |.|..:..|...| |..:|.:..|:||||:......||     :
 Worm    65 LFVLGIFGN------------GGVLWAVARNKRLQSARNVFLLNLIFTDLILVFTAIPVTPWYAM 117

Human    90 LASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGL 154
            ...:|....:..|.|.|.:|:.|   :|.:||.      |::|:::|.|..|  .::.||....|
 Worm   118 TKDWAFGSVMCHLVPLSNSCSVF---VTSWSLT------AISLDKFLHINDP--TKQPVSIRQAL 171

Human   155 AVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYL---------------QLYATLL 204
            |:..:|:.||.|. :||.|...::|.   |:: :::.|.|.|.               ::|.|.:
 Worm   172 AITFLIWIVSTLI-NLPYLMSFEHVD---GSF-YVQPGETPYCGHFCDEANWQSENSRKIYGTTV 231

Human   205 LLL-----IVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLI 264
            :||     :..:..|.|. ||..:......:.::...||..       ::|.:..|..::.::::
 Worm   232 MLLQFVVPMAVITYCYFK-ILQKVSKDMIIQNAQFCQSLTQ-------KQRSDATSRKKKVNYIL 288

Human   265 LLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRP 320
            :  .|.:||..|.||.|:...:.:.....| |..:...|.:||:.:......:..|
 Worm   289 I--AMVVTFIGCWLPLTLLNLVKDFKKEPE-WLKRQPFFWAINAHVIAMSLVVWNP 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTGER2	NP_000947.2	7tm_1	38..314	CDD:278431	69/301 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	231..253		3/21 (14%)
npr-5	NP_001024265.1	7tmA_NPYR-like	56..347	CDD:320331	72/316 (23%)
		TM helix 1	58..82	CDD:320331	6/28 (21%)
		TM helix 2	91..113	CDD:320331	8/21 (38%)
		TM helix 3	129..151	CDD:320331	9/30 (30%)
		TM helix 4	172..188	CDD:320331	6/16 (38%)
		TM helix 5	225..248	CDD:320331	5/22 (23%)
		TM helix 6	282..307	CDD:320331	7/26 (27%)
		TM helix 7	323..347	CDD:320331	4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910