Protein Alignment PTGER2 and nmur-2

DIOPT Version :9

• Sequence 1: NP_000947.2
• Gene: PTGER2 / 5732
• HGNCID: 9594
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_493666.2
• Gene: nmur-2 / 173398
• WormBaseID: WBGene00019616
• Length: 403
• Species: Caenorhabditis elegans
• Alignment Length: 411
• Identity: 78/411 - (18%)
• Similarity: 160/411 - (38%)
• Gaps: 118/411 - (28%)

Human    11 EDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELV 75
            |.|::...:.|  :..|...:|..|:.||:....::|      ...|....::..||.:.|::::
 Worm    23 ERCQSAGIVIP--TVIIYGTIFLLGLFGNICTCIVIA------ANKSMHNPTNYYLFSLAVSDII 79

Human    76 FTDLLGTCLISPVVLASYARNQTLVALAP---ESRACTYFAFAMTFFSLATMLMLFAMALERYLS 137
                   .||..:.:..|   |:|....|   ....|...||.:.|.|.|:::::...:.||:|:
 Worm    80 -------ALILGLPMEFY---QSLDYSYPYRFSEGICKARAFLIEFTSYASIMIICCFSFERWLA 134

Human   138 IGHPYFYQRRVSRSGGLAVLPVIYAVSLLF-CSLPL--------LDYGQYVQYCPGT-------- 185
            |.||  .:.::..:...|.:.:|.|.::.| |:||:        |...:..:|.|.|
 Worm   135 ICHP--LRSKIFSTLWRANVLIILAWTISFVCALPIAFIVQINKLPLPEDAKYQPWTNKVSTDGI 197

Human   186 ------WCFIRHGR---TAYLQLYATLLLLLI----VSVLACNFSVILNLIRMHRRSRRSRCGPS 237
                  :|.:...|   ...:.::|..:..:|    :.::..:.:|.|....:..:
 Worm   198 FVLHTEFCAMNQSRPDQQKMIIIFAFTVFFVIPAIAIVIMYAHIAVQLESSEIDLK--------- 253

Human   238 LGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPF------TIFAYMNETSSRKEKW 296
                    |.:...:|.:.:..|...:||::: |||.:|.|||      :::...:||::..
 Worm   254 --------GDKMVKKRRNKSNRTVLKMLLSVV-ITFFICWLPFHIQRLLSVYTTWSETTTIS--- 306

Human   297 DLQALRFLSI------------NSIIDPWVFAILRPPVLRLMRSVLCCRISLRT----------- 338
              ..::|||:            ||..:|.::.||.    :..||..|     ||
 Worm   307 --PPVQFLSMIVFYISGFCYYSNSAANPILYNILS----QKYRSAFC-----RTILGDHIANFVF 360

Human   339 ----QDATQTSCSTQSDASKQ 355
                :......||:.::|.::
 Worm   361 KGHQRPGQSKRCSSSTEAEQR 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTGER2	NP_000947.2	7tm_1	38..314	CDD:278431	62/326 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	231..253		1/21 (5%)
nmur-2	NP_493666.2	7tmA_capaR	32..346	CDD:320262	70/360 (19%)
		TM helix 1	34..58	CDD:320262	6/29 (21%)
		TM helix 2	67..89	CDD:320262	5/28 (18%)
		TM helix 3	107..129	CDD:320262	5/21 (24%)
		TM helix 4	152..168	CDD:320262	5/15 (33%)
		TM helix 5	216..239	CDD:320262	2/22 (9%)
		TM helix 6	267..292	CDD:320262	10/25 (40%)
		TM helix 7	314..339	CDD:320262	4/24 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910