Protein Alignment PTGER1 and CG7497

DIOPT Version :9

• Sequence 1: NP_000946.2
• Gene: PTGER1 / 5731
• HGNCID: 9593
• Length: 402
• Species: Homo sapiens
• Sequence 2: NP_001287100.1
• Gene: CG7497 / 39966
• FlyBaseID: FBgn0036742
• Length: 412
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 98/422 - (23%)
• Similarity: 168/422 - (39%)
• Gaps: 61/422 - (14%)

Human     7 LNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAA 71
            |:|.:...:||.|.|     .|:..:.....:.:..|.||...|.|||.:||:     ::....:
  Fly     8 LDLLMPHNSTTVAPP-----KALYANRNRLIIGVIIMVLGVFGNSLALFILAR-----KKLNKNS 62

Human    72 TFLLFVASLLATDLAGHVIPGAL---VLRLYTAGRAPAGGACHFLGGCMV--FFGLCPLLLGCGM 131
            .:.|.:..|...:|.  .:.|.|   :|::|.:.............|.:|  ||||....:...|
  Fly    63 KYTLMLRCLATNNLV--ALLGMLTTTLLKMYLSKEVLQSFIRVDCVGLVVWRFFGLSSGCIAAVM 125

Human   132 AVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRY--ELQYPGTWCFIGLGP 194
            |.||.:.:.||.::...::....|.::.::..:|:.:..||....|.|  |.......|......
  Fly   126 AAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDA 190

Human   195 PGGWRQALLAGLFASLGLVALLAALVCNTLSGLALL----RARWRRR-------SRRPPPASGPD 248
            ||.|.:. .|.||...|.:..:..:.||......||    |:|..:|       ||....|...|
  Fly   191 PGVWNKT-YAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAISID 254

Human   249 SRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMV-------------GQLV 300
                     |.|:|.::... ...||..|.|..|....|...|.|.:.             .:|:
  Fly   255 ---------PESSSGTTLYQ-TQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLM 309

Human   301 GIMVVS-CICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLR-QAVLRQLL 363
            ..:.:| .|||.|.::.:.||:......:..:...:|..|.:.:...||:||:|.| :::...||
  Fly   310 AFLSISFVICWMPQMIAIPLAIAPNRVPASNKFFIIADVLTALHFTSDPYVYVLSRSKSINWSLL 374

Human   364 RLLPP-RAGAKGGPAGLGLTPSAWEASSLRSS 394
            ..:.. |:|.:.|    ||..|..:.|.:|::
  Fly   375 GCIKRWRSGWRPG----GLRRSQSDQSRMRTT 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTGER1	NP_000946.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..266		7/27 (26%)
		7tm_1	<280..351	CDD:278431	16/84 (19%)
CG7497	NP_001287100.1	7tm_4	36..>221	CDD:304433	45/192 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144959
Domainoid	1	1.000	52	1.000	Domainoid score	I11441
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8162
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412827at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11866
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.860