DRSC/TRiP Functional Genomics Resources

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Protein Alignment PTGDR and npr-5

DIOPT Version :9

Sequence 1:NP_000944.1 Gene:PTGDR / 5729 HGNCID:9591 Length:359 Species:Homo sapiens
Sequence 2:NP_001024265.1 Gene:npr-5 / 190386 WormBaseID:WBGene00021983 Length:433 Species:Caenorhabditis elegans


Alignment Length:358 Identity:83/358 - (23%)
Similarity:140/358 - (39%) Gaps:76/358 - (21%)


- Green bases have known domain annotations that are detailed below.


Human    29 TGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRS- 92
            |.|.|.|..||:....|:.|...|..| |.|...:.:..|..|||:......||. ..||..:. 
 Worm    59 TFLYGFLFVLGIFGNGGVLWAVARNKR-LQSARNVFLLNLIFTDLILVFTAIPVT-PWYAMTKDW 121

Human    93 -----LRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALV 152
                 :..|.| |.|| |..|.         ::..|.|::|:.:|.:..|  .::.:::|....:
 Worm   122 AFGSVMCHLVP-LSNS-CSVFV---------TSWSLTAISLDKFLHINDP--TKQPVSIRQALAI 173

Human   153 APVVSAFSLAFCALPF-MGF----GKF-VQ-----YCPGTWCFIQMVHEEGSLSVLGYSVLYSSL 206
            ..::...| ....||: |.|    |.| ||     || |.:|.......|.|..:.|.:|:....
 Worm   174 TFLIWIVS-TLINLPYLMSFEHVDGSFYVQPGETPYC-GHFCDEANWQSENSRKIYGTTVMLLQF 236

Human   207 MALLVLATVLCNLGAMRNLYAMHRRLQR--------HPRSCTRDCAEPRADGREASPQPLEELDH 263
            :..:.:.|           |...:.||:        :.:.|.....:.|:|.....    :::::
 Worm   237 VVPMAVIT-----------YCYFKILQKVSKDMIIQNAQFCQSLTQKQRSDATSRK----KKVNY 286

Human   264 LLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRS 328
            :|:  .|.|.|..|.||:   ......||.|      :|.|.|:...|...|:.....:.::..:
 Worm   287 ILI--AMVVTFIGCWLPL---TLLNLVKDFK------KEPEWLKRQPFFWAINAHVIAMSLVVWN 340

Human   329 PVFRIFFHKIFIRPLRYRSRCS---NSTNMESS 358
            |:  :||   ::...:.||..|   |||.:.||
 Worm   341 PL--LFF---WLTRKQKRSGLSKILNSTEIVSS 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PTGDRNP_000944.1 7tmA_PGD2 17..335 CDD:320268 73/330 (22%)
TM helix 1 18..44 CDD:320268 6/14 (43%)
TM helix 2 61..87 CDD:320268 6/25 (24%)
TM helix 3 105..135 CDD:320268 6/29 (21%)
TM helix 4 147..169 CDD:320268 4/22 (18%)
TM helix 5 195..224 CDD:320268 3/28 (11%)
TM helix 6 258..288 CDD:320268 7/29 (24%)
TM helix 7 302..327 CDD:320268 5/24 (21%)
npr-5NP_001024265.1 7tmA_NPYR-like 56..347 CDD:320331 75/335 (22%)
TM helix 1 58..82 CDD:320331 8/22 (36%)
TM helix 2 91..113 CDD:320331 6/22 (27%)
TM helix 3 129..151 CDD:320331 9/32 (28%)
TM helix 4 172..188 CDD:320331 2/16 (13%)
TM helix 5 225..248 CDD:320331 4/33 (12%)
TM helix 6 282..307 CDD:320331 7/29 (24%)
TM helix 7 323..347 CDD:320331 5/28 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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