Protein Alignment PTGDR and srx-28

DIOPT Version :9

• Sequence 1: NP_000944.1
• Gene: PTGDR / 5729
• HGNCID: 9591
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_503749.3
• Gene: srx-28 / 187606
• WormBaseID: WBGene00005919
• Length: 301
• Species: Caenorhabditis elegans
• Alignment Length: 186
• Identity: 39/186 - (20%)
• Similarity: 62/186 - (33%)
• Gaps: 77/186 - (41%)

Human    87 YAQNRSLRVLAPALDNS--------------LCQAFAFFM---------------SFFG------ 116
            ||.|::     |::..|              :|..:..|:               .:||
 Worm    27 YAINKT-----PSMSGSFGIITKSQVVCNMIMCSIYILFVLPLQLSSLSHFIPISHYFGTAAQTV 86

Human   117 -----LSSTLQLL----AMALECWLSLGHPF------FYRRHITLRLGALVAPVVSAFSLAFCAL 166
                 ||..|..|    |:.:..|.:  |.|      |||..|.:            ||:.||..
 Worm    87 YIISNLSHFLNALNRCCALFMPLWYT--HIFSNSKTVFYRNFIWI------------FSIIFCIT 137

Human   167 PFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGY-------SVLYSSLMALLVLATV 215
            .:..|..|:.|.|.:|.| |.|.......:..|       |::..:|:..|::|.|
 Worm   138 LYEFFKCFLLYAPKSWSF-QFVQNPVCNQITWYLDFNFNCSIIIITLIIDLLVAFV 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTGDR	NP_000944.1	7tmA_PGD2	17..335	CDD:320268	39/186 (21%)
		TM helix 1	18..44	CDD:320268
		TM helix 2	61..87	CDD:320268	39/186 (21%)
		TM helix 3	105..135	CDD:320268	10/59 (17%)
		TM helix 4	147..169	CDD:320268	4/21 (19%)
		TM helix 5	195..224	CDD:320268	6/28 (21%)
		TM helix 6	258..288	CDD:320268
		TM helix 7	302..327	CDD:320268
srx-28	NP_503749.3	TM helix 1	9..32	CDD:341315	3/4 (75%)
		7TM_GPCR_Srx	12..272	CDD:370981	39/186 (21%)
		TM helix 2	39..65	CDD:341315	2/25 (8%)
		TM helix 3	77..106	CDD:341315	7/28 (25%)
		TM helix 4	119..136	CDD:341315	7/28 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D412827at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010