DRSC/TRiP Functional Genomics Resources

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Protein Alignment PTGDR and srx-23

DIOPT Version :9

Sequence 1:NP_000944.1 Gene:PTGDR / 5729 HGNCID:9591 Length:359 Species:Homo sapiens
Sequence 2:NP_503293.3 Gene:srx-23 / 185164 WormBaseID:WBGene00005914 Length:294 Species:Caenorhabditis elegans


Alignment Length:307 Identity:62/307 - (20%)
Similarity:113/307 - (36%) Gaps:71/307 - (23%)


- Green bases have known domain annotations that are detailed below.


Human    68 LTVTDLLGKCLLSPVVLAA----YAQNRSLRVLAP--ALDN-SLCQAFAFFM------------- 112
            :|.|.:.|..:|:..||||    .:.|.|..::..  |:.| ::|..:...:             
 Worm    10 ITFTIMFGGIILNLFVLAAARNMSSMNGSFGIITKNHAICNLTMCLLYVLVVCPMQLSNIPILIT 74

Human   113 --SFFGLS-------STLQLLAMALECWLSLGHPFFYRRHITL----------RLGALVAPVVSA 158
              .:.||:       |.:..|.|||..:.::   |:|.|:..:          ..|.||      
 Worm    75 NSRYIGLASIILHECSNMLSLLMALNRFFAV---FWYLRYNRIFSNSNTTFMKNFGGLV------ 130

Human   159 FSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYS-VLYSSLMALLVLATVLCNLGAM 222
            |::.:..| :...|.|..|...::.| .:|......||..|| :|:::   .||:.|:..||..:
 Worm   131 FAVIYYIL-YDYLGCFFYYEKSSYTF-WLVDTPLCYSVSWYSDILFNN---SLVVFTLAINLITV 190

Human   223 RNLYAMHRRL------QRHPRSCTRDCA---EPRADGREASPQPLEELDHLLLLALMTVLFTMCS 278
            ......:|.|      |...|:..|:..   :..|.|..............:.:....:||.:.|
 Worm   191 YKAGKSNRNLLQAAGAQMTKRNRQRELGFIKQSFAQGAVIFGGQCVYYVGAVFVTNSVLLFFITS 255

Human   279 LPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFII 325
            |.|...|..|.|..:..        :::|:.......||..|::..:
 Worm   256 LWVFVHAIQGGFMLISN--------QEMRSAMSKKQNSIASPFVVTV 294

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PTGDRNP_000944.1 7tmA_PGD2 17..335 CDD:320268 62/307 (20%)
TM helix 1 18..44 CDD:320268
TM helix 2 61..87 CDD:320268 8/22 (36%)
TM helix 3 105..135 CDD:320268 8/51 (16%)
TM helix 4 147..169 CDD:320268 5/21 (24%)
TM helix 5 195..224 CDD:320268 10/29 (34%)
TM helix 6 258..288 CDD:320268 6/29 (21%)
TM helix 7 302..327 CDD:320268 4/24 (17%)
srx-23NP_503293.3 TM helix 1 9..32 CDD:341315 8/21 (38%)
7TM_GPCR_Srx 12..272 CDD:370981 57/273 (21%)
TM helix 2 39..65 CDD:341315 3/25 (12%)
TM helix 3 76..106 CDD:341315 7/32 (22%)
TM helix 4 119..139 CDD:341315 5/26 (19%)
TM helix 5 169..190 CDD:341315 8/23 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D412827at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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