DRSC/TRiP Functional Genomics Resources

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Protein Alignment PTGDR and octr-1

DIOPT Version :9

Sequence 1:NP_000944.1 Gene:PTGDR / 5729 HGNCID:9591 Length:359 Species:Homo sapiens
Sequence 2:NP_001024569.1 Gene:octr-1 / 184469 WormBaseID:WBGene00006411 Length:408 Species:Caenorhabditis elegans


Alignment Length:283 Identity:69/283 - (24%)
Similarity:106/283 - (37%) Gaps:68/283 - (24%)


- Green bases have known domain annotations that are detailed below.


Human    31 LLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRV 95
            :.||||.:..:.|.       |.||.....:  |:..|.|.|:|...|:.|:.|       :..:
 Worm    36 IFGNLLVVVTVYRD-------RKLRMQRQNW--LIVSLAVADMLVGLLVMPLTL-------TYEI 84

Human    96 LAP-ALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHIT-LRLGALVAPVVSA 158
            :.. .:.|.||:.:......|..:|.|.:.|::|:.:.|:..|..|....| ||:...:. |...
 Worm    85 VGEWTMGNILCEIWLALDVLFVTASILHICAISLDRYFSVTSPLTYPATRTPLRMFIYIG-VSWI 148

Human   159 FSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSV---LGYSVLYSSLMALLVLATVLCNLG 220
            .||..|..|..|           |   :....||..||   ||| ||||||.:..:...:|..:.
 Worm   149 VSLLICLPPIFG-----------W---RPERAEGECSVSTDLGY-VLYSSLGSFYIPVVILIIVY 198

Human   221 AMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRA 285
            |  .:|::   ..||.|...::               .|..||.|     .:|....|....|..
 Worm   199 A--KIYSI---TIRHSRQRLKE---------------TERRDHTL-----NMLTIRSSTNERYNM 238

Human   286 YY------GAFKDVKEKNRTSEE 302
            .|      ...:|.|||..|:.:
 Worm   239 EYELEENSDPIEDEKEKVVTNRD 261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PTGDRNP_000944.1 7tmA_PGD2 17..335 CDD:320268 69/283 (24%)
TM helix 1 18..44 CDD:320268 4/12 (33%)
TM helix 2 61..87 CDD:320268 8/25 (32%)
TM helix 3 105..135 CDD:320268 7/29 (24%)
TM helix 4 147..169 CDD:320268 6/21 (29%)
TM helix 5 195..224 CDD:320268 13/31 (42%)
TM helix 6 258..288 CDD:320268 8/35 (23%)
TM helix 7 302..327 CDD:320268 0/1 (0%)
octr-1NP_001024569.1 7tmA_alpha2_AR 22..389 CDD:320187 69/283 (24%)
TM helix 1 24..48 CDD:320187 4/11 (36%)
TM helix 2 58..80 CDD:320187 7/23 (30%)
TM helix 3 96..118 CDD:320187 4/21 (19%)
TM helix 4 141..157 CDD:320187 4/16 (25%)
TM helix 5 176..199 CDD:320187 10/23 (43%)
TM helix 6 322..347 CDD:320187
TM helix 7 357..382 CDD:320187
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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