Protein Alignment PTGDR and srx-18

DIOPT Version :9

• Sequence 1: NP_000944.1
• Gene: PTGDR / 5729
• HGNCID: 9591
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_507493.2
• Gene: srx-18 / 183532
• WormBaseID: WBGene00005909
• Length: 293
• Species: Caenorhabditis elegans
• Alignment Length: 171
• Identity: 38/171 - (22%)
• Similarity: 65/171 - (38%)
• Gaps: 50/171 - (29%)

Human    60 VFYMLVCGLTVTD----LLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST 120
            :|.:.||.:..:|    :....:|....:||| :...|..|..|| |..|..|
 Worm    56 IFLLYVCPMQFSDSTIFIQYSHILGASAMAAY-EISHLSHLLTAL-NRFCAVF------------ 106

Human   121 LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAF---SLAFCALPFMGFGKFVQYCPGTW 182
                           .||:|.: :..::|.::  ::.|.   |:.||.|.:...|....|...||
 Worm   107 ---------------FPFYYEK-LFSKIGTII--MIQAIWIVSIIFCVLFYEIIGCLFTYDDVTW 153

Human   183 CFIQMVHEEGSLSVLGYSVL--YSS--LMALLVLATVLCNL 219
            .|       |.|:....|.|  |:.  |..::::.|::.||
 Worm   154 TF-------GFLTTQKCSQLTWYTDFILNTVMIIVTIVVNL 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTGDR	NP_000944.1	7tmA_PGD2	17..335	CDD:320268	38/171 (22%)
		TM helix 1	18..44	CDD:320268
		TM helix 2	61..87	CDD:320268	6/29 (21%)
		TM helix 3	105..135	CDD:320268	2/29 (7%)
		TM helix 4	147..169	CDD:320268	6/24 (25%)
		TM helix 5	195..224	CDD:320268	7/29 (24%)
		TM helix 6	258..288	CDD:320268
		TM helix 7	302..327	CDD:320268
srx-18	NP_507493.2	TM helix 1	10..32	CDD:341315
		7TM_GPCR_Srx	12..272	CDD:370981	38/171 (22%)
		TM helix 2	39..65	CDD:341315	3/8 (38%)
		TM helix 3	77..106	CDD:341315	10/30 (33%)
		TM helix 4	119..138	CDD:341315	5/20 (25%)
		TM helix 5	164..188	CDD:341315	7/24 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910