Protein Alignment PTEN and ptn1

DIOPT Version :10

• Sequence 1: NP_001291646.4
• Gene: PTEN / 5728
• HGNCID: 9588
• Length: 576
• Species: Homo sapiens
• Sequence 2: NP_596312.1
• Gene: ptn1 / 2541101
• PomBaseID: SPBC609.02
• Length: 348
• Species: Schizosaccharomyces pombe
• Alignment Length: 191
• Identity: 71/191 - (37%)
• Similarity: 108/191 - (56%)
• Gaps: 8/191 - (4%)

Human   177 IIKEIVSRNKRRYQEDGFD-----LDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKN 236
            |::.:|||.::..:::..:     ||:.||...:|||..||..:..:|||:..||.::|.::.|:
pombe     3 ILRSVVSRGRKGLKQEKVNRSFAYLDMVYITSKVIAMSTPAAGIHKLYRNDELDVFKYLTTQLKD 67

Human   237 HYKIYNLCAERH-YDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAG 300
            ::.:.|||||.. |....|...|..|.|:|||||.|..:.....::|............:|||||
pombe    68 NWILLNLCAEETVYHLELFKPNVINYGFQDHNPPPLLFLWAIVMNMDALFQTQPLLTLVVHCKAG 132

Human   301 KGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDY 361
            |||||.:||:||:..|. |.|:::|:.|.|.|.....|:||.||.|||||.. :||...:|
pombe   133 KGRTGTVICSYLVAFGG-LTAKQSLELYTEKRMVRGHGLTISSQIRYVYYIE-ILKQFPNY 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTEN	NP_001291646.4	PTP_PTEN	197..354	CDD:350359	63/157 (40%)
		PTEN_C2	361..522	CDD:463081	1/1 (100%)
ptn1	NP_596312.1	PTP_PTEN-like	28..185	CDD:350347	63/158 (40%)