Protein Alignment pld1b and Pld

DIOPT Version :9

• Sequence 1: XP_021326023.1
• Gene: pld1b / 572492
• ZFINID: ZDB-GENE-070510-3
• Length: 1042
• Species: Danio rerio
• Sequence 2: NP_001137610.1
• Gene: Pld / 35554
• FlyBaseID: FBgn0286511
• Length: 1364
• Species: Drosophila melanogaster
• Alignment Length: 1235
• Identity: 455/1235 - (36%)
• Similarity: 641/1235 - (51%)
• Gaps: 248/1235 - (20%)

Zfish    18 DMTDIMEN-------LDTRELDIGDGEDEFDGQDPNSTDSR--IPFSAVY----KTKGFKEPGAR 69
            |...|:.|       ::.:|.|  |.|:|||.::.||...|  |||:::|    |...|:.   :
  Fly   166 DSVTILSNVGDKPVLVERKETD--DDEEEFDDEENNSVVLRHEIPFTSIYGPSVKFNSFQR---K 225

Zfish    70 VFLTALPITAKILEVERFTSAQDRFNITAQRSVSKVL--PAVFKIEMKHGNFTWMVKRKEKHFME 132
            ||:....|..:|::.|              |||:..|  |.::.||:.||.|.|.:||:.|||..
  Fly   226 VFIPGREIHVRIVDTE--------------RSVTTHLLNPNLYTIELTHGPFKWTIKRRYKHFNS 276

Zfish   133 LHRELRAYKTFLRIPLPSRSHTERRQTI------------------------------------- 160
            ||::|..::|.|.||.|||||.|:|.|:
  Fly   277 LHQQLSFFRTSLNIPFPSRSHKEKRTTLKATAREMADESTLKDLPSHTKVKQTSTPLRAEGRSSK 341

Zfish   161 ---------------------------------NRNLERHMPTLPRGGGEELAREEQVSSRKRQL 192
                                             .:..:|.:|..| ...|.|...|.:|.|.:||
  Fly   342 IAGSNANNAMAMISPNHSSILAGLTPRRIQKKRKKKKKRKLPRFP-NRPESLVTVENLSVRIKQL 405

Zfish   193 EDYLNKLLKMPMYRNYHATMEFIDVSQLSFIHDLGPKGLEGMVHKRSGGHRIPG----------- 246
            ||||..||.:.:||::|.|:.|::||.:||:..:|.||.||::.||:|..| ||
  Fly   406 EDYLYNLLNISLYRSHHETLNFVEVSNVSFVPGMGIKGKEGVILKRTGSTR-PGQAGCNFFGCFQ 469

Zfish   247 LNCCGHSK------MCYRWSKRWMVAKDSCLLLMKPDSGAISFVLLVDKEFDIKMDTKDTETKHG 305
            .|||....      :|..|..||...|::|...::|..|:|..|:|.|:.||:......|..:.|
  Fly   470 KNCCVRCNYFCSDVVCGTWRNRWFFVKETCFGYIRPTDGSIRAVILFDQGFDVSTGIYQTGMRKG 534

Zfish   306 VRIDSLSRTLVLKFTSYRHARWWGQAVDDFVRKYGSNFLKDHRFGSFANEQKNILSKWYVNGKQY 370
            :::.:.:|.:|||..:.|..:.|.|.:.:....|..:|...:...|||..:.|..:.|||:|.||
  Fly   535 LQVLTNNRHIVLKCWTRRKCKEWMQYLKNTANSYARDFTLPNPHMSFAPMRANTHATWYVDGAQY 599

Zfish   371 MEDVANALEEAEEEIFITDWWLSPEIFLKRPVVEGNRWRLDSILKRQAQKGVRIFVMLYKEVELA 435
            |..||:.||.|.|||:|.||||||||::|||.::|:.||||.||.|:|::|||:||:||||||:|
  Fly   600 MSAVADGLEAALEEIYIADWWLSPEIYMKRPALDGDYWRLDKILLRKAEQGVRVFVLLYKEVEMA 664

Zfish   436 LGINSEYSKRTLLQLHPNIKVMRHPDHVSSSVYLWAHHEKIVVIDQSVAFVGGIDLAYGRWDDRE 500
            |||||.|||.||.: |.||||||||||....:.|||||||||||||:.||:|||||.||||||..
  Fly   665 LGINSYYSKSTLAK-HENIKVMRHPDHARGGILLWAHHEKIVVIDQTYAFMGGIDLCYGRWDDHH 728

Zfish   501 HRLTDIGSV--------TRTLP----------------VSAENASEASPAMAAPSNG-------- 533
            |||||:||:        ||..|                .|:.||...:.|...|.:.
  Fly   729 HRLTDLGSISTSSFSGSTRRTPSLYFTKDDTDSAFGSRKSSRNAHYDTSAKERPPSPPPDEPNTS 793

Zfish   534 --------------PSAALANGKNVPADTA---DQPKLKGHGKPKKTRFSIRRHLQK-------- 573
                          ||..:::....||::.   :..||   ..|:..|.::...|:.
  Fly   794 IELKTLKPGDRLLIPSTLVSSPGETPAESGIALEGMKL---NTPEMERKNVLDRLKNNAMKGARM 855

Zfish   574 -----HRPTSGDS------VSSVESSEE------------------KSEATQDLQADVIGLMGNT 609
                 ||.|:.::      |.::||.|.                  .:.:||.|..    ..|..
  Fly   856 GKDFMHRLTATETEEKSAEVYTIESEEATDHEVNLNMASGGQEVAITTSSTQILSE----FCGQA 916

Zfish   610 RFWHGKDYCNFVHKDWIQLDKPFDDFIDRHITPRMPWHDIASVVHGQAARDVARHFIQRWNFTKI 674
            ::|.||||.||:.|||:.|:.||.|.|||..||||||||:...|.|.:|||||||||||||..|:
  Fly   917 KYWFGKDYSNFILKDWMNLNSPFVDIIDRTTTPRMPWHDVGLCVVGTSARDVARHFIQRWNAMKL 981

Zfish   675 MKPKYRSLSYPYLLPKSHTTANEIKYQV---PGCTQ-----TNVQVLRSASDWSAGI---KYHEE 728
            .|.: .:..:|||:|||:       :||   |...|     ...|:|||.|.||.|.   ...|:
  Fly   982 EKLR-DNTRFPYLMPKSY-------HQVRLNPNIQQNRQQRVTCQLLRSVSAWSCGFIEADLVEQ 1038

Zfish   729 SIHTAYVNAIEHSQHYIYIENQFFISC-------ADSKVVHNRIGDAIAKRIIKAYRDGKKYRVY 786
            |||.||:..|..:|||:||||||||:.       .....|.|:||:.:.|||::|:::.|.:|||
  Fly  1039 SIHDAYIQTITKAQHYVYIENQFFITMQLGMGVPGAYNNVRNQIGETLFKRIVRAHKERKPFRVY 1103

Zfish   787 VVTPLLPGFEGDINTGGGSAIQAVMHFNYRTMIRGDCSIISQLKKEMGDQWINYISFGGLRTHAE 851
            |:.|||||||||:....|.|::|:.|:||.::.||..||:::|::.......|||||..||.|:.
  Fly  1104 VIMPLLPGFEGDVGGSTGIAVRAITHWNYASISRGRTSILTRLQEAGIANPENYISFHSLRNHSF 1168

Zfish   852 LEGRLVTELIYVHSKMLIADDNTVIIGSANINDRSMLGKRDSEVAVIYEDIHTVKSVMDGQEYQA 916
            |....:|||||||||:|||||..||.||||||||||:||||||:|.|..|.......|:|::|.:
  Fly  1169 LNNTPITELIYVHSKLLIADDRVVICGSANINDRSMIGKRDSEIAAILMDEEFEDGRMNGKKYPS 1233

Zfish   917 GPFGLSLRLECFRMILG-----ANTDPSIDVTDPISDQFYKEVWMSTAARNATIYQRVFRCLPSS 976
            |.|...||...|:..||     .::...:|:.||:.::|:...|...:.:|..||..||:|:|:.
  Fly  1234 GVFAGRLRKYLFKEHLGLLESEGSSRSDLDINDPVCEKFWHGTWRRISMQNTEIYDEVFKCIPTD 1298

Zfish   977 DVRTILELDSFLSKPGLDKEDPARAQEELKKIRGFLVQFPLQFLSEQNLLPPIGSKEAMVPMEVW 1041
            .|:|...|..:..:|.|.|..|..|......|:|:||..||:||:::.|.||..|||.::|..||
  Fly  1299 FVKTFASLRKYQEEPPLAKTAPDLAANRANDIQGYLVDLPLEFLNKEVLTPPGTSKEGLIPTSVW 1363

Zfish  1042  1041
              Fly  1364  1363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pld1b	XP_021326023.1	PLN03008	67..1027	CDD:331186	428/1157 (37%)
Pld	NP_001137610.1	PX_PLD	230..431	CDD:132805	55/215 (26%)
		PH_PLD	419..564	CDD:269956	45/145 (31%)
		PLDc_vPLD1_2_yPLD_like_1	590..734	CDD:197236	99/144 (69%)
		PLDc_vPLD1_2_yPLD_like_2	1032..1220	CDD:197239	95/187 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587183
Domainoid	1	1.000	187	1.000	Domainoid score	I3265
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	751	1.000	Inparanoid score	I547
OMA	1	1.010	-	-		QHG58673
OrthoDB	1	1.010	-	-		D330134at33208
OrthoFinder	1	1.000	-	-		FOG0001475
OrthoInspector	1	1.000	-	-		otm24539
orthoMCL	1	0.900	-	-		OOG6_100567
Panther	1	1.100	-	-	O	PTHR18896
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1041
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770