Protein Alignment PSPH and aay

DIOPT Version :10

• Sequence 1: NP_004568.2
• Gene: PSPH / 5723
• HGNCID: 9577
• Length: 225
• Species: Homo sapiens
• Sequence 2: NP_524001.2
• Gene: aay / 39085
• FlyBaseID: FBgn0023129
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 215
• Identity: 109/215 - (50%)
• Similarity: 150/215 - (69%)
• Gaps: 1/215 - (0%)

Human     9 KLFYSADAVCFDVDSTVIREEGIDELAKICGVEDAVSEMTRRAMGGAVPFKAALTERLALIQPSR 73
            |:...:..||||||||||.||||||||:.||....|:.:|:.|||||:.|:.||..||.:|:|::
  Fly    56 KVIQQSQIVCFDVDSTVICEEGIDELAEYCGKGSEVARVTKEAMGGAMTFQDALKIRLNIIRPTQ 120

Human    74 EQVQRLIAEQPPHLTPGIRELVSRLQERNVQVFLISGGFRSIVEHVASKLNIPATNVFANRLKFY 138
            :||:..|.|:|..|:..::..||.|:....||:||||||..::..||::|.||..||:||::.|.
  Fly   121 QQVRDFIQERPSTLSKNVKRFVSHLKAEGKQVYLISGGFDCLIAPVANELGIPLKNVYANKMLFD 185

Human   139 FNGEYAGFDETQPTAESGGKGKVIKLL-KEKFHFKKIIMIGDGATDMEACPPADAFIGFGGNVIR 202
            :.|||..||..|||:.||||.:.|.|: ||......|.||||||||:||.|||:.||||||||:|
  Fly   186 YLGEYDSFDINQPTSRSGGKAEAIALIRKENSDDSLITMIGDGATDLEAVPPANYFIGFGGNVVR 250

Human   203 QQVKDNAKWYITDFVELLGE 222
            .:|...|::|:|||.:|:|:
  Fly   251 PEVYRRAQYYVTDFEQLMGQ 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSPH	NP_004568.2	HAD_PSP_eu	15..216	CDD:319801	104/201 (52%)
aay	NP_524001.2	HAD_PSP_eu	62..264	CDD:319801	104/201 (52%)