Protein Alignment JPH2 and Jph2

DIOPT Version :10

• Sequence 1: NP_065166.2
• Gene: JPH2 / 57158
• HGNCID: 14202
• Length: 696
• Species: Homo sapiens
• Sequence 2: NP_001033063.1
• Gene: Jph2 / 296345
• RGDID: 1305196
• Length: 692
• Species: Rattus norvegicus
• Alignment Length: 702
• Identity: 614/702 - (87%)
• Similarity: 643/702 - (91%)
• Gaps: 16/702 - (2%)

Human     1 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWS 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWS 65

Human    66 QGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQ 130
            ||||||||||||||||||||||||||||||||||::|||||||||||||||||||||||||||||
  Rat    66 QGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSTNSGAKYEGTWNNGLQDGYGTETYADGGTYQ 130

Human   131 GQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAI 195
            ||||||||||||||||||||||||||||||||||||||||||||||||   |||:|||.||.|.:
  Rat   131 GQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPD---SPAADGPTLPLPPV 192

Human   196 PRGGFALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGSQRSRVSFLKSDLSSGASDA 260
            |||||||||||.|| |||.|   |||.||||||:|||:|||||:||||||:|||||:||||||||
  Rat   193 PRGGFALSLLATAE-AARPP---GLFTRGALLGRLRRSESRTSLGSQRSRLSFLKSELSSGASDA 253

Human   261 ASTASLGEAAEGADE-AAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRH 324
            |||.||.|.|||.|: ||||:||||||||||||||||||||||||||||||||||||||||||||
  Rat   254 ASTGSLAEGAEGPDDAAAPFDADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRH 318

Human   325 GYGCTTLPDGHREEGKYRHNVLVKDTKRRMLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAAS 389
            |||.||||||||||||||||||||.||||:|.||||||||||||.||||||||||||||||||||
  Rat   319 GYGRTTLPDGHREEGKYRHNVLVKGTKRRVLPLKSNKVRQKVEHGVEGAQRAAAIARQKAEIAAS 383

Human   390 RTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPD 454
            ||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||.:
  Rat   384 RTSHAKAKAEAAEQAALAANQESNIARTLAKELAPDFYQPGPEYQKRRLLQEILENSESLLEPRE 448

Human   455 RGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGE 519
            ||.| .|||:.|||||||||||||:||||.||||||||||||||||.|||||||||||||||.||
  Rat   449 RGPG-TGLPERPRESPQLHERETPQPEGGPPSPAGTPPQPKRPRPGSSKDGLLSPGAWNGEPGGE 512

Human   520 GSRSVTPSEGAGRRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFED- 583
            |||..|||:|||||||||||:|.|||||||.|||||||||||||:|||||||||.||||||.||
  Rat   513 GSRPATPSDGAGRRSPARPASEHMAIEALQPPPAPSREPEVALYRGYHSYAVRTGPPEPPPLEDE 577

Human   584 -QPEPEVSGSESAPSSPATAPLQ---APTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARG 644
             :|||||..|:|.|.||.:|.:|   :|..|...||:  ||.||||||:|||||:||||||||||
  Rat   578 PEPEPEVPRSDSEPPSPVSATVQEEESPAPRSRVPAK--PATLEPKPIVPKAEPKAKARKTEARG 640

Human   645 LTKAGAKKKARKEAALAAEAEVEVEEVPNTILICMVILLNIGLAILFVHLLT 696
            |:|||||||.|||.|..|||||||||||||:|||||||||||||||||||||
  Rat   641 LSKAGAKKKGRKEVAQEAEAEVEVEEVPNTVLICMVILLNIGLAILFVHLLT 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JPH2	NP_065166.2	COG4642	<2..143	CDD:443680	138/140 (99%)
		MORN 1. /evidence=ECO:0000255	14..36		21/21 (100%)
		MORN 2. /evidence=ECO:0000255	38..59		20/20 (100%)
		MORN 3. /evidence=ECO:0000255	60..79		18/18 (100%)
		MORN 4. /evidence=ECO:0000255	82..104		19/21 (90%)
		PLN03185	101..>334	CDD:215619	204/233 (88%)
		MORN 5. /evidence=ECO:0000255	106..128		21/21 (100%)
		MORN 6. /evidence=ECO:0000255	129..151		21/21 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	164..193		23/28 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	250..282		24/32 (75%)
		MORN 7. /evidence=ECO:0000255	291..313		21/21 (100%)
		MORN 8. /evidence=ECO:0000255	314..336		20/21 (95%)
		Bipartite nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q9ET78	351..365		11/13 (85%)
		PHA03247	<444..642	CDD:223021	155/202 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	448..652		160/208 (77%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q9ET78	495..499		3/3 (100%)
Jph2	NP_001033063.1	COG4642	<2..143	CDD:443680	138/140 (99%)
		MORN 1. /evidence=ECO:0000255	14..36		21/21 (100%)
		PLN03185	38..>328	CDD:215619	266/296 (90%)
		MORN 2. /evidence=ECO:0000255	38..59		20/20 (100%)
		MORN 3. /evidence=ECO:0000255	60..79		18/18 (100%)
		MORN 4. /evidence=ECO:0000255	82..104		19/21 (90%)
		MORN 5. /evidence=ECO:0000255	106..128		21/21 (100%)
		MORN 6. /evidence=ECO:0000255	129..151		21/21 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	164..190		23/28 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	246..273		20/26 (77%)
		MORN 7. /evidence=ECO:0000255	285..307		21/21 (100%)
		MORN 8. /evidence=ECO:0000255	308..330		20/21 (95%)
		Bipartite nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q9ET78	345..359		11/13 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	439..661		172/224 (77%)
		PHA03247	<446..633	CDD:223021	142/189 (75%)
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:Q9ET78	488..492		3/3 (100%)