Protein Alignment ADCK1 and adck1

DIOPT Version :9

• Sequence 1: NP_001353416.1
• Gene: ADCK1 / 57143
• HGNCID: 19038
• Length: 580
• Species: Homo sapiens
• Sequence 2: NP_001116521.1
• Gene: adck1 / 100144553
• ZFINID: ZDB-GENE-080401-5
• Length: 521
• Species: Danio rerio
• Alignment Length: 575
• Identity: 362/575 - (62%)
• Similarity: 428/575 - (74%)
• Gaps: 62/575 - (10%)

Human     1 MARKALKLASWTSMALAASGIYFYSNKYLDPNDFGAVRVGRAVATTAVISYDYLTSLKSVPYGSE 65
            ||.:.||::|..:...|:||.|.|| |.:|.||...||.|||.||||||||||||:|:.|.||:|
Zfish     1 MAVRLLKVSSVATAVFASSGFYLYS-KNVDYNDLSIVRFGRAAATTAVISYDYLTTLRDVQYGTE 64

Human    66 EYLQLRSKVHLRSARRLCELCCANRGTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEI 130
            ||..::||||.|||.||.:|||||||||||||||||||:||||||||||||:|||:||.|||:.|
Zfish    65 EYWAVKSKVHRRSAERLLDLCCANRGTFIKVGQHLGALEYLLPEEYTSTLKILHSRAPHSSMEHI 129

Human   131 RQVIREDLGKEIHDLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEV 195
            |||||||||||:.|||..||:||.|.|||||||||||.||||||||||||||:.||||||::||.
Zfish   130 RQVIREDLGKELSDLFIQFDETPHGAASLAQVHKAVLPDGRTVAVKVQHPKVQRQSSKDIVVMEF 194

Human   196 LVLAVKQLFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERV 260
            |:..|..|||:|.|||||:|||||:|||||||||||||||::.||:.|.|||:|:|||||||:|:
Zfish   195 LLQVVHWLFPDFAFMWLVEEAKKNMPLELDFLNEGRNAEKIADMLKQFSFLKIPKIHWDLSTKRI 259

Human   261 LLMEFVDGGQVNDRDYMERNKIDVNEVRSRAQGCCAGERGLGQGCPGSACVSRSSEKVSHLLSAN 325
            |.|:|.:|||||||:||.|:.|:||
Zfish   260 LTMDFAEGGQVNDREYMRRHGINVN---------------------------------------- 284

Human   326 DFSSSYHVQALSALATIEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVLLDHG 390
                             ||||:|||:||||||||||||||||||||||||.|.:.|.||||||||
Zfish   285 -----------------EISRNLGKIYSEMIFVNGFVHCDPHPGNVLVRKSPESNKTEIVLLDHG 332

Human   391 LYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRLGAGDLYPLFACMLTARSWDSVNRGISQAPV 455
            |||:|.::|||:||.||||||..|:|.::.||:|||||||||||||:||||||.|||.||||.||
Zfish   333 LYQVLNQDFRLDYCRLWQSLIKGDLKGIERYSRRLGAGDLYPLFACVLTARSWTSVNAGISQTPV 397

Human   456 TATEDLEIRNNAANYLPQISHLLNHVPRQMLLILKTNDLLRGIEAALGTRASASSFLNMSRCCIR 520
            |.:||:|||.|||.||||||.|||.:||||||:|||||||||||..|.||||:|||:||||||.|
Zfish   398 TQSEDVEIRTNAALYLPQISELLNRIPRQMLLLLKTNDLLRGIETILQTRASSSSFINMSRCCTR 462

Human   521 ALAEHKKKNTCSFFRRTQISFSEAFNLWQINLHELILRVKGLKLADRVLALICWL 575
            |:|.||:....|..||.:|..||.::|.||||:||:|.::...||    ..:|:|
Zfish   463 AVARHKRSKASSRSRRVRIWLSERWSLCQINLYELVLWLRSSALA----RCLCYL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADCK1	NP_001353416.1	ADCK1-like	117..426	CDD:270871	184/308 (60%)
adck1	NP_001116521.1	AarF	67..>369	CDD:223733	225/358 (63%)
		ADCK1-like	116..368	CDD:270871	184/308 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194331677
Domainoid	1	1.000	371	1.000	Domainoid score	I5341
eggNOG	1	0.900	-	-		E1_COG0661
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6493
Inparanoid	1	1.050	719	1.000	Inparanoid score	I4097
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG57752
OrthoDB	1	1.010	-	-		D155590at7742
OrthoFinder	1	1.000	-	-		FOG0000919
OrthoInspector	1	1.000	-	-		oto42007
orthoMCL	1	0.900	-	-		OOG6_100510
Panther	1	1.100	-	-	LDO	PTHR43173
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3709
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	16	16.310