DRSC/TRiP Functional Genomics Resources

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Protein Alignment PSMD8 and Rpn12

DIOPT Version :10

Sequence 1:NP_002803.2 Gene:PSMD8 / 5714 HGNCID:9566 Length:350 Species:Homo sapiens
Sequence 2:NP_648904.1 Gene:Rpn12 / 39845 FlyBaseID:FBgn0028693 Length:264 Species:Drosophila melanogaster


Alignment Length:259 Identity:130/259 - (50%)
Similarity:186/259 - (71%) Gaps:3/259 - (1%)


- Green bases have known domain annotations that are detailed below.


Human    94 MYEQLKGEWNRKSPNLSKCGEELGRLKLVLLELNFLPTTG--TKLTKQQLILARDILEIGAQWSI 156
            :|::|..||:::.||..|||:.|.:||:.|:::.||||.|  .:.:|:||||||.:||:..:.|:
  Fly     7 LYKELTAEWSKRPPNTVKCGQLLDQLKVALVKMAFLPTDGNDAQSSKKQLILARSVLEVAVEHSV 71

Human   157 LRKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLPAKDIQ 221
            |.||:.:||||||||||||:||.:.:.||...::|||||||:|||.|||::||||||.|....||
  Fly    72 LSKDLLAFERYMAQLKCYYYDYAKIIGESESKYKLLGLNLLYLLSGNRVSDFHTELELLSVDVIQ 136

Human   222 TNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFTE 286
            .|.:|:..::||||:|||.|||:|.||..:|.|.|::|:|:||:|:||||..||||:|:||...:
  Fly   137 HNQFIRPILALEQYIMEGRYNKIFQAKSTVPVEVYSYFMDLLLETVRDEIGACIEKSYDKISAKD 201

Human   287 ATRILFFNTPKKMTDYAKKRGWVLGPNNYYSFASQQQKPEDTTIPSTELAKQVIEYARQLEMIV 350
            |.:.|....|.::..:..||.|.|..:..|||..:..||:: .:||.|||:||:.|||.|||||
  Fly   202 AAKRLNLRVPDEIKAFGAKRQWKLEASGDYSFTDRSVKPKE-LLPSEELAEQVLSYARDLEMIV 264

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PSMD8NP_002803.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
CSN8_PSD8_EIF3K 201..315 CDD:462954 54/113 (48%)
Rpn12NP_648904.1 CSN8_PSD8_EIF3K 119..229 CDD:462954 52/109 (48%)
Blue background indicates that the domain is not in the aligned region.

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