DRSC/TRiP Functional Genomics Resources

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Protein Alignment PSMD8 and Rpn12R

DIOPT Version :10

Sequence 1:NP_002803.2 Gene:PSMD8 / 5714 HGNCID:9566 Length:350 Species:Homo sapiens
Sequence 2:NP_996086.1 Gene:Rpn12R / 2768973 FlyBaseID:FBgn0036465 Length:262 Species:Drosophila melanogaster


Alignment Length:262 Identity:108/262 - (41%)
Similarity:166/262 - (63%) Gaps:4/262 - (1%)


- Green bases have known domain annotations that are detailed below.


Human    92 TGMYEQLKGEWNRKSPNLSKCGEELGRLKLVLLELNF--LPTTGTKLTKQQLILARDILEIGAQW 154
            :.:|.:||.||::.:|||:.|...|...||.|:..||  :.|..:...|.|||.:|::|||..:.
  Fly     2 SNLYTELKNEWSKHAPNLTHCSRLLDGFKLELVRSNFGTIQTASSSKQKDQLIKSREMLEIAVEH 66

Human   155 SILRKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLPAKD 219
            ||..||..:||||||||..||:||.:.|..|.:|::.:|||||::|:.||:|:||.||||||...
  Fly    67 SITIKDYAAFERYMAQLNTYYYDYDKYLESSKHMYKFMGLNLLYMLATNRLADFHIELERLPTAL 131

Human   220 IQTNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKIL- 283
            :..:.:|:..::||.|.|||.|||:..||.::|:|.|:.|:|||::|.|:|||.|:||:|.|:. 
  Fly   132 LLHDSFIQPVLALENYYMEGRYNKILQAKKSMPSEIYSNFMDILVNTAREEIASCMEKSYLKMAP 196

Human   284 FTEATRILFFNTPKKMTDYAKKRGWVLGPNNYYSFASQQQKPEDTTIPSTELAKQVIEYARQLEM 348
            ...|.|:......|::.:.|.||.|.|.....|.:|....:|.: .:|:.::|...:.||::||.
  Fly   197 KLAAQRLGLRPGSKELFELATKRQWCLDEEGNYDYAGLHTRPME-KVPAKDIATHNLTYAQELEK 260

Human   349 IV 350
            ||
  Fly   261 IV 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PSMD8NP_002803.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
CSN8_PSD8_EIF3K 201..315 CDD:462954 48/114 (42%)
Rpn12RNP_996086.1 CSN8_PSD8_EIF3K 98..228 CDD:462954 55/129 (43%)
Blue background indicates that the domain is not in the aligned region.

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