Protein Alignment PSMD7 and RPN8

DIOPT Version :10

• Sequence 1: NP_002802.2
• Gene: PSMD7 / 5713
• HGNCID: 9565
• Length: 324
• Species: Homo sapiens
• Sequence 2: NP_014904.3
• Gene: RPN8 / 854435
• SGDID: S000005787
• Length: 338
• Species: Saccharomyces cerevisiae
• Alignment Length: 333
• Identity: 157/333 - (47%)
• Similarity: 230/333 - (69%)
• Gaps: 19/333 - (5%)

Human     7 QKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLD 71
            :||.:.||||||.:||:.|. :....||.|||:||......:.|:||||:||:||:|:..|||||
Yeast     6 EKVTIAPLVLLSALDHYERT-QTKENKRCVGVILGDANSSTIRVTNSFALPFEEDEKNSDVWFLD 69

Human    72 HDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNS-VLVIIDVKPKDLGLPT 135
            |:|:|||..|.||:||:|:::||||:||||..:|:.||||.|:|..|: :|:|:|||.:.:||||
Yeast    70 HNYIENMNEMCKKINAKEKLIGWYHSGPKLRASDLKINELFKKYTQNNPLLLIVDVKQQGVGLPT 134

Human   136 EAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKG 200
            :||:::|:|.||||.|.|||.|:...|.||||||:||||||||::|...|.||.|:|||:..|||
Yeast   135 DAYVAIEQVKDDGTSTEKTFLHLPCTIEAEEAEEIGVEHLLRDVRDQAAGGLSIRLTNQLKSLKG 199

Human   201 LNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQE-----------------FVKA 248
            |.|||.|:..||:||...:|||||.|:.:|||||||||::...:                 ..||
Yeast   200 LQSKLKDVVEYLDKVINKELPINHTILGKLQDVFNLLPNLGTPDDDEIDVENHDRINISNNLQKA 264

Human   249 FYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKS 313
            ..:||||:::|:|:::|:||::|..:||.|||.|:..:::..::|:....|..|.:..||:....
Yeast   265 LTVKTNDELMVIYISNLVRSIIAFDDLIENKIQNKKIQEQRVKDKQSKVSDDSESESGDKEATAP 329

Human   314 DVKKEEKK 321
            .::::.||
Yeast   330 LIQRKNKK 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSMD7	NP_002802.2	MPN_RPN7_8	7..285	CDD:163693	150/295 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..324		8/41 (20%)
RPN8	NP_014904.3	MPN_RPN7_8	6..303	CDD:163693	150/297 (51%)