Protein Alignment PSMD7 and Rpn8

DIOPT Version :10

• Sequence 1: NP_002802.2
• Gene: PSMD7 / 5713
• HGNCID: 9565
• Length: 324
• Species: Homo sapiens
• Sequence 2: NP_001261167.1
• Gene: Rpn8 / 37894
• FlyBaseID: FBgn0002787
• Length: 358
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 256/342 - (74%)
• Similarity: 297/342 - (86%)
• Gaps: 18/342 - (5%)

Human     1 MP--ELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKK-VLDVSNSFAVPFDEDD 62
            ||  |::|.||:|||||||||||||||:||:||||||||||||.|:.| ||||||||||||||||
  Fly     1 MPSQEVSVNKVIVHPLVLLSVVDHFNRMGKIGNQKRVVGVLLGCWRSKGVLDVSNSFAVPFDEDD 65

Human    63 KDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVK 127
            ||.|||||||||||||||||||||||||:|||||||||||:||||||||::||||||||||||.|
  Fly    66 KDKSVWFLDHDYLENMYGMFKKVNARERVVGWYHTGPKLHQNDIAINELVRRYCPNSVLVIIDAK 130

Human   128 PKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRIT 192
            |||||||||||||||||||||:|||||||||.||||||||||||||||||||||||||:|||:||
  Fly   131 PKDLGLPTEAYISVEEVHDDGSPTSKTFEHVPSEIGAEEAEEVGVEHLLRDIKDTTVGSLSQKIT 195

Human   193 NQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQM 257
            ||:.||||||::|.||:.||::|...|:||||||:|||||:||||||::..:|....|:||||||
  Fly   196 NQLMGLKGLNAQLRDIKQYLQRVGDSKMPINHQIVYQLQDIFNLLPDITNDQFTGTMYVKTNDQM 260

Human   258 VVVYLASLIRSVVALHNLINNKIANRDAEK-----KEGQEKEESKKDR--KEDKEKD--KDKEKS 313
            :||||||::||::|||||||||:||||||:     ||.:||.:..||:  ||.|:||  |.:||:
  Fly   261 LVVYLASMVRSIIALHNLINNKLANRDAEEGKSDSKEAKEKNKDSKDKDNKETKDKDGKKAEEKA 325

Human   314 DVKKEE------KKEKK 324
            |..|:|      |.|:|
  Fly   326 DKGKDEGGKGSRKXERK 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSMD7	NP_002802.2	MPN_RPN7_8	7..285	CDD:163693	229/278 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..324		25/57 (44%)
Rpn8	NP_001261167.1	MPN_RPN7_8	9..290	CDD:163693	231/280 (83%)