Protein Alignment NUP107 and Nup107

DIOPT Version :10

• Sequence 1: NP_065134.1
• Gene: NUP107 / 57122
• HGNCID: 29914
• Length: 925
• Species: Homo sapiens
• Sequence 2: NP_609446.1
• Gene: Nup107 / 34481
• FlyBaseID: FBgn0027868
• Length: 845
• Species: Drosophila melanogaster
• Alignment Length: 855
• Identity: 293/855 - (34%)
• Similarity: 452/855 - (52%)
• Gaps: 67/855 - (7%)

Human   116 SQRSGLFTNT-----EPHSITEDVTI--------SAVMLRED-----DPGEA---ASMSMFSDFL 159
            |.||||...|     .|.:::..:.|        :.:.|.||     |.|::   .....|.|.|
  Fly     9 SSRSGLLRTTLNSSMPPQNLSHSLLILEKSNAEQNELSLMEDTGDDLDRGKSRMDVLFPQFFDVL 73

Human   160 QSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLAS 224
            |:  :.:....|::::....:|...|..|...:.....|.|...:..|||..|:||:.|||||.:
  Fly    74 QA--QGNGQEAFEVIQSLTQVCRGVVEQLELEIDHGMGGEQGARQRESMLTWLRQEINTWRLLHA 136

Human   225 LYRDRI----QSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFS 285
            |:.|||    ....::|.....| :..|||.|::.|:..::.:|:.||||||||  |..:.||..
  Fly   137 LFYDRILLQTDRQADDEMQDGPT-LGGSEKEVIQQLYALNATLREYQLVVDWLE--ACYDRGEQQ 198

Human   286 DNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYL 350
            :.:..:.:.:.|||||..|:..|..:: |....:||.||||||:|:|.||..||.||.:||.:.:
  Fly   199 NPLHAHDRMMAWENTLFQLENLQGAAF-GKGHKIVTRLDPDAPVREKRPLHALDEEDNLRLSRAI 262

Human   351 FTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGT----ELEPVEGNPYRRIWKISC 411
            |.|||||..::..:|||..||.||||.||||:|:.|||.....    |..|:||||.|.|||...
  Fly   263 FELIRAGRVDDGLKLCKHFGQTWRAAILEGWRLHEDPNFEQNVSVLHEKLPIEGNPRRDIWKRCA 327

Human   412 WRMAEDELFNRYERA---IYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLD 473
            |.:|:.:.::.|.||   :::...|:||.||.  ..|.|.:||:.:|.:|..||.||:.  ..|.
  Fly   328 WMLADSKNYDEYSRATAGVFSGHLGSLKTLLH--SNWHDLLWAHLKVQIDIRVESEIRG--CCLK 388

Human   474 ETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKS 538
            ..:.:|.:|.....|:|::||||.......|.:..|....|:|:.|||.....|:....:|:.|.
  Fly   389 NYQPMPDDYWNGRMTMEQIFEELNVAKDASVRDFAQSQLGIIQRHLILDTCGELIQHMVRWVEKD 453

Human   539 RNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVA 603
            .:....|.||||.|::||.|.:|...:|..:.:::..|::.||......|||:||..|...|.|.
  Fly   454 TSQQSPHQLRFMAHIVLFLRQIGRVEQERQAEKIVAAYVEALIARGEPQLIAYYTASLSNPLQVQ 518

Human   604 QYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIR--KKDNGEFSHHDLAPALDTGTTE 666
            .|:.|||.|.:...|...::.|.:|.|||..||:..|:|||  .:..|||...      .:|...
  Fly   519 LYSRFLEQVEQKRPRELAVDAALQAGLDVEQITRVTVQNIRLAHQPLGEFGEP------QSGEIS 577

Human   667 E-DRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQ 730
            . |:.||..::||:..|.||.|.|.|.||::|.:|||.|.|..::.|..:|.|.:.::.:.   .
  Fly   578 AIDQRKISALEWLIHLPEQRGELLWQANAMIRTYLASSKVECMRQTFRMVPADIVQQLVSL---Y 639

Human   731 GMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKP----ALIPQPTFTEKVAHEHK 791
            |....:|..::..::|:||.:|||...::|.||.:...:.|:||    |...|..|||::|.|.|
  Fly   640 GSVDNIPPREECCLKEYLCYKAYLSGVDSFVEWNRLQQNRPKKPQTSHAASSQDNFTERMASERK 704

Human   792 EKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVD-----VREDAKE---DHERTHQMVL 848
            |:.:..:...|:..:........|.:||||:|.|.||:||     :.|:|.:   || |..||..
  Fly   705 EQAHRSEVVRWEHKVKEQAKQTIELLYNVLMFPDKGWLVDPFIAKLPENAVQLSWDH-RLLQMEK 768

Human   849 LRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLD 913
            ||.:|:|.:...|:.::..:|.:..|::|||.:|||..:||.|::|.:|.:||.|:.::||.||:
  Fly   769 LRSICIPEIALFLNEVMFKSGDFAGCVRLADEISSENRQLYKVYTKHKLAELLAKIADASLELLN 833

Human   914 QGLDPLGYEI 923
            ..|||.||.|
  Fly   834 SKLDPWGYPI 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUP107	NP_065134.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..66
		Nup84_Nup100	209..908	CDD:461184	258/724 (36%)
Nup107	NP_609446.1	Nup84_Nup100	121..828	CDD:461184	258/724 (36%)