Protein Alignment C12orf4 and RGD1311164

DIOPT Version :9

• Sequence 1: NP_001291740.1
• Gene: C12orf4 / 57102
• HGNCID: 1184
• Length: 552
• Species: Homo sapiens
• Sequence 2: NP_001100093.1
• Gene: RGD1311164 / 297607
• RGDID: 1311164
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 519/552 - (94%)
• Similarity: 535/552 - (96%)
• Gaps: 0/552 - (0%)

Human     1 MKKNRERFCNREREFVYKFKVGSQCLELRVPLKFPVQENASHLHGRLMLLHSLPCFIEKDLKEAL 65
            ||||||||.::||||||||::||:.|||||||:|||.|||||||||||||||||||||.||||||
  Rat     1 MKKNRERFSSKEREFVYKFQIGSERLELRVPLRFPVDENASHLHGRLMLLHSLPCFIENDLKEAL 65

Human    66 TQFIEEESLSDYDRDAEASLAAVKSGEVDLHQLASTWAKAYAETTLEHARPEEPSWDEDFADVYH 130
            .:|||||||.|:|.||||.|.|||||||||||||||||||||||||||||||||:||||||||||
  Rat    66 ARFIEEESLRDHDSDAEACLEAVKSGEVDLHQLASTWAKAYAETTLEHARPEEPNWDEDFADVYH 130

Human   131 DLIHSPASETLLNLEHNYFVSISELIGERDVELKKLRERQGIEMEKVMQELGKSLTDQDVNSLAA 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 DLIHSPASETLLNLEHNYFVSISELIGERDVELKKLRERQGIEMEKVMQELGKSLTDQDVNSLAA 195

Human   196 QHFESQQDLENKWSNELKQSTAIQKQEYQEWVIKLHQDLKNPNNSSLSEEIKVQPSQFRESVEAI 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.:|.
  Rat   196 QHFESQQDLENKWSNELKQSTAIQKQEYQEWVIKLHQDLKNPNNSSLSEEIKVQPSQFRESADAA 260

Human   261 GRIYEEQRKLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRSGVKLHRLQTALSLYSTSL 325
            |||||||||||||||||||||||||||||||||||||||||||...|||||||||||||||||||
  Rat   261 GRIYEEQRKLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRTQGSGVKLHRLQTALSLYSTSL 325

Human   326 CGLVLLVDNRINSYSGIKRDFATVCQECTDFHFPRIEEQLEVVQQVVLYARTQRRSKLKESLDSG 390
            ||||||||||||||||||||||||||||||||||||||||||||||.||||||||||.||:.|||
  Rat   326 CGLVLLVDNRINSYSGIKRDFATVCQECTDFHFPRIEEQLEVVQQVALYARTQRRSKCKEARDSG 390

Human   391 NQNGGNDDKTKNAERNYLNVLPGEFYITRHSNLSEIHVAFHLCVDDHVKSGNITARDPAIMGLRN 455
            |||||:|:|:|||||||||:||||||||||||||||||||||||||:||||||||||||||||||
  Rat   391 NQNGGSDEKSKNAERNYLNILPGEFYITRHSNLSEIHVAFHLCVDDNVKSGNITARDPAIMGLRN 455

Human   456 ILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLRRAELVFKCVKGFMMEMASWDGGISRTVQFLV 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 ILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLRRAELVFKCVKGFMMEMASWDGGISRTVQFLV 520

Human   521 PQSISEEMFYQLSNMLPQIFRVSSTLTLTSKH 552
            ||||||||||||||||||||||||||||||||
  Rat   521 PQSISEEMFYQLSNMLPQIFRVSSTLTLTSKH 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C12orf4	NP_001291740.1	DUF2362	41..546	CDD:313393	480/504 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..403		13/19 (68%)
RGD1311164	NP_001100093.1	DUF2362	41..546	CDD:401963	480/504 (95%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83695834
Domainoid	1	1.000	967	1.000	Domainoid score	I1699
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10685
Inparanoid	1	1.050	1046	1.000	Inparanoid score	I5080
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG52561
OrthoDB	1	1.010	-	-		D100824at32523
OrthoFinder	1	1.000	-	-		FOG0007202
OrthoInspector	1	1.000	-	-		oto141250
orthoMCL	1	0.900	-	-		OOG6_106014
Panther	1	1.100	-	-	LDO	PTHR16525
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5311
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	16.410