Protein Alignment PCBP4 and Imp

DIOPT Version :10

• Sequence 1: XP_047304568.1
• Gene: PCBP4 / 57060
• HGNCID: 8652
• Length: 426
• Species: Homo sapiens
• Sequence 2: NP_001245616.1
• Gene: Imp / 32009
• FlyBaseID: FBgn0285926
• Length: 638
• Species: Drosophila melanogaster
• Alignment Length: 444
• Identity: 109/444 - (24%)
• Similarity: 180/444 - (40%)
• Gaps: 97/444 - (21%)

Human    43 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERITTITGSTAAVFHAVSMIA 103
            ||:|:..:.||:|||::|.|::.|.:||.||:.:    :.||. |:..||.|:.....:|...|.
  Fly   145 LRILVQSEMVGAIIGRQGSTIRTITQQSRARVDVHRKENVGSL-EKSITIYGNPENCTNACKRIL 208

Human   104 FKLDEDLCAAPANGGNVSR--PPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVA--GDL 164
            ..:.::  |...|.|.:|.  ..:.|:::...:..|.:|||:|..||.|.:.|..::.|:  .|:
  Fly   209 EVMQQE--AISTNKGELSPECSEICLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSSINDI 271

Human   165 LPNSTERAVTVSGVPDAIILCVRQICAVILES--------PPKGATIP-YHPSLSLGT----VLL 216
            ...:.||.:||.|:.:.:.....||...:.:|        .|:....| .||...:.|    ::.
  Fly   272 NSFNLERIITVKGLIENMSRAENQISTKLRQSYENDLQAMAPQSLMFPGLHPMAMMSTPGNGMVF 336

Human   217 SANQGF-SVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVI 280
            :.:..| |.|....:.|||                  ||||.:.|.....:....:||:.:|.:|
  Fly   337 NTSMPFPSCQSFAMSKTPA------------------SVVPPVFPNDLQETTYLYIPNNAVGAII 383

Human   281 GRQGSKISEIRQMSGAHIKIG-----NQAEGAGERHVTITGSPVSIALAQYLI------------ 328
            |.:||.|..|.:.|.|.:||.     ...:...||.|||.|:|.....|||:|
  Fly   384 GTRGSHIRSIMRFSNASLKIAPLDADKPLDQQTERKVTIVGTPEGQWKAQYMIFEKMREEGFMCG 448

Human   329 ------TACLETAKSTSG-----------------GTPSSAPADLPAPFSPPLTALPTAPPGLLG 370
                  |..|..|.|..|                 |:....|..   ..:||.......|..::|
  Fly   449 TDDVRLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEH---ALAPPSGGDEETPVHIIG 510

Human   371 TPYAISLSNFIGLKPMPFLALPPASPGPPPGLAAYTAKMAAANGSKKAERQKFS 424
            ..|::..:.    :.:..:.|   |..|||    .|.|..||....:.::|..:
  Fly   511 LFYSVQSAQ----RRIRAMML---STNPPP----ITKKQKAAKEQLQQQQQSLA 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PCBP4	XP_047304568.1	KH-I_PCBP4_rpt1	40..109	CDD:411945	23/69 (33%)
		KH-I_PCBP4_rpt2	124..195	CDD:411948	19/72 (26%)
		KH-I_PCBP4_rpt3	264..331	CDD:411951	25/89 (28%)
Imp	NP_001245616.1	RRM2_VICKZ	42..118	CDD:409794
		KH-I_IGF2BP_rpt1	144..211	CDD:411828	23/66 (35%)
		KH-I_IGF2BP_rpt2	231..302	CDD:411829	19/70 (27%)
		KH-I_IGF2BP_rpt3	368..437	CDD:411830	23/68 (34%)
		KH-I_IGF2BP_rpt4	455..523	CDD:411831	12/74 (16%)