Protein Alignment TBX20 and Tbx20

DIOPT Version :10

• Sequence 1: NP_001071121.1
• Gene: TBX20 / 57057
• HGNCID: 11598
• Length: 447
• Species: Homo sapiens
• Sequence 2: NP_919239.1
• Gene: Tbx20 / 57246
• MGIID: 1888496
• Length: 445
• Species: Mus musculus
• Alignment Length: 655
• Identity: 136/655 - (20%)
• Similarity: 214/655 - (32%)
• Gaps: 140/655 - (21%)

Human   240 LKQALEEENSTILHRYHSPCQERSRS-PTVNGENKSPLLLS----------DSCSLPDLTTPLKK 293
            |.:.|:|.|||.|....|...|:.|| ...:..|.:.:.||          |..|.|.....:::
Mouse  1688 LDEGLDEANSTFLLEETSETLEKIRSFNLTHCRNAAEIQLSSAVSVLEKVEDEISKPYRNNQIRR 1752

Human   294 RRLYQLLDTAYSESSTPTPSPYATPTHTDITPTDPAFATPPRIKSDDETYRNGYKPIYSPVTPVT 358
            ..:...|:|..........|.|...||.:         ...|:..|                 :.
Mouse  1753 ENISTTLNTHNLSLQQVQESLYTAKTHNN---------QSRRLLQD-----------------IQ 1791

Human   359 PGTPGNTMHFENISSPESSPEIKRCTYNQEGYDRPSNMLTLGPFRNSNLTELGLQEIKT-IGYTS 422
            ..|...|:...|:||.....|    |..||..|..::.|.:....::..|.  |.|:|. :...|
Mouse  1792 SNTHTLTISRNNVSSLNHELE----TQVQEAQDLLTDALNIAEDMDNGATT--LDELKNDLELWS 1850

Human   423 PRSRTEVNRPCPGEKESVSDLQLGLDAVEPAALQKSMETPAHDRTEP-SNQLDSTHSGRGTMYSS 486
            |..|..|:             .|.:|..:..|||  :...|.|..:. |.|..:.:|....:.|:
Mouse  1851 PSLRKHVD-------------SLVMDLTKRDALQ--LVYRAEDHAQALSKQAQALNSSLSEVSSA 1900

Human   487 WVKSPDRTGVNFSVNSNLR---DLTPSHQLETGGGFRVSESKCLIQQDDTR-----GMFLGAAVF 543
            .|.....|..|.::..|::   ||..:..........::.   |.:|:..|     .:...||:.
Mouse  1901 SVNISIATRTNANIRENIQLAADLALAANQNASSALNMTS---LTEQEKRRLQKSSEILDRAALL 1962

Human   544 CTSEDGLASGFG-------------RTVNDNLIDGSCTPQNPPQKKKVSLLEYRKRQREARKSGS 595
            ....|||.....             :.....|.:.....:|.|:..:..:|:. |:|.||..:..
Mouse  1963 KNHTDGLMQNVSAVTSRLSLVAANIQNFTQMLPEALGILRNLPEGSRAEILQV-KQQTEAANASL 2026

Human   596 KPENFALISVSPHPSGSLSSSGDGCVHSSENGEQAENQASLPLPPPAAAAAATAAAAYSASSEEG 660
            :.....|.........|.|:.|     |::|..|..||.       ...:..||.||.|..||
Mouse  2027 QEALERLRDYRLKLDESSSALG-----SADNSTQRTNQL-------LRDSQDTANAAGSRLSE-- 2077

Human   661 SSNCPVKDANSSEKKDP--EVQWTASTSVEQVRERSYQRALLLSDHRKDKDS-----GGESPCVS 718
               ..||.....|:..|  .:..|.|.::..:||       |:|..||...|     ..:..||.
Mouse  2078 ---ADVKADRLLERLKPLQTLGETLSRNLSDIRE-------LISQARKQAASIKVAVSADRNCVR 2132

Human   719 CSPSHVQSPPSSHSNHIPQVHAQSLAPSLSELMADPDAEGTEATSTSECPSP---DTSQSPSKTS 780
            .....|   .||:.|.:......|...:|...|....:|...|....:....   |.....::..
Mouse  2133 AYRPEV---TSSNFNTLTLTMKTSEPDNLLFYMGSSSSEDFMALEMHDGKVSFLWDAGSGHNRLE 2194

Human   781 KPGSPGPINPAQSHGKILTKPDSHWEATATVSEADNSVHQNPEPQHRQLSSNTPALSQNHAPQAH 845
            .|..  .||..:.|....|:...|  ||.||.:.|:      ||        .||:..:.|..|.
Mouse  2195 YPDV--QINNDKWHRINATRFGRH--ATLTVQQTDS------EP--------LPAVKSSAAGSAT 2241

Human   846 ALSAN 850
            .:..|
Mouse  2242 VMDVN 2246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX20	NP_001071121.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..81
		T-box_TBX20-like	100..289	CDD:410319	17/59 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..340		3/23 (13%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<337..>409	CDD:476819	12/71 (17%)
Tbx20	NP_919239.1	T-box_TBX20-like	99..288	CDD:410319
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..337
		P-loop containing Nucleoside Triphosphate Hydrolases	<319..>407	CDD:476819