Protein Alignment TBX20 and byn

DIOPT Version :10

• Sequence 1: NP_001071121.1
• Gene: TBX20 / 57057
• HGNCID: 11598
• Length: 447
• Species: Homo sapiens
• Sequence 2: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Alignment Length: 458
• Identity: 140/458 - (30%)
• Similarity: 202/458 - (44%)
• Gaps: 132/458 - (28%)

Human    69 GGSGSSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTI 133
            ||:||                   |:|....:..||:.:|||.:|..|..|||:||:||||||.:
  Fly    75 GGAGS-------------------PNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVV 120

Human   134 RVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLK 198
            ::|.||:||.|.|.||::.|.:|:.|::|.  ...|:..|||:.|....:||||:||..|...:|
  Fly   121 KISASGLDPAAMYTVLLEFVQIDSHRWKYV--NGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMK 183

Human   199 QMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTA 263
            :.:||.||||| |:.:.:|.|:|||:|||:||||:::        :..:.....|:.||||.|.|
  Fly   184 EPISFAKVKLT-NKTNGNGQIMLNSLHKYEPRVHLVR--------VGSEQRHVVTYPFPETQFIA 239

Human   264 VTAYQNQLITKLKIDSNPFAKGFRDSSRLTD-------------------------IERESVESL 303
            ||||||:.:|.|||..|||||.|.|:....|                         :......|:
  Fly   240 VTAYQNEEVTSLKIKYNPFAKAFLDAKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLSI 304

Human   304 IQKHS------------------------YARS-------PIRTY----------GGEEDVLGDE 327
            .|.|.                        |.||       |.||.          .|.....|:.
  Fly   305 AQSHGLVASCPSVSSAESVGPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNA 369

Human   328 SQTTPNRGSAFTTSDNL------SLSSWVSSSS-----SFP-----GFQHPQS--LTALGTSTAS 374
            |.|:|...||..|..:|      |:|:.|||||     |.|     ...:.||  ::...:.|||
  Fly   370 SSTSPQPPSAPQTPTSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTAS 434

Human   375 I---------------ATPIPHPIQGSLPPYSRLGMPLTPSAI--ASSMQGSGPTFPSFHM-PRY 421
            :               ||.:|.|:..::.....:....:||..  :.|...|.|::...|: |..
  Fly   435 VFSYPSSWQSNGNYWNATSVPGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHS 499

Human   422 HHY 424
            |.|
  Fly   500 HQY 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX20	NP_001071121.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..81		4/11 (36%)
		T-box_TBX20-like	100..289	CDD:410319	87/188 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..340		8/33 (24%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<337..>409	CDD:476819	24/106 (23%)
byn	NP_524031.2	T-box_TBXT_TBX19-like	87..264	CDD:410318	87/187 (47%)