Protein Alignment TBX20 and ocm

DIOPT Version :10

• Sequence 1: NP_001071121.1
• Gene: TBX20 / 57057
• HGNCID: 11598
• Length: 447
• Species: Homo sapiens
• Sequence 2: NP_611894.1
• Gene: ocm / 37874
• FlyBaseID: FBgn0266083
• Length: 2175
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 111/593 - (18%)
• Similarity: 180/593 - (30%)
• Gaps: 205/593 - (34%)

Human     4 TASPKPQLSSRANAFSIA-----ALMSSGGSKEKEATENTIKPLEQFVEKSSCAQPLGELTSLDA 63
            |.|.||.......|.|:|     |..||.|......|..|         .|:..:.....|.:.:
  Fly  1498 TKSSKPSAGGYPIAASVATSTTSAFASSSGKSTPVCTAKT---------NSASTKNKSSATGIRS 1553

Human    64 HGEFGGGSGSS------------------------------PSSSSLCTEPLIPTTPIIPSEEMA 98
            :.||...:.:.                              ||.|.:.:...|.:...:..|...
  Fly  1554 NIEFRKVNHNDVDELQIPELHQTDHRWVVLDIFDDFSHIFVPSFSDMISLTRIHSVMQVAEERQK 1618

Human    99 KIACSLETKELWDKFHELGTEMIITKSGRR----------MFPTIRVSFSGVDPEAKYIVLMDI- 152
            .:.........:|.|        :|.|.::          |.|.:.|....||   :.::|.::
  Fly  1619 VVKLQFFPNAPYDAF--------VTPSSKKKIYFGPLSLDMPPPVLVLLQSVD---RKMMLREVY 1672

Human   153 -----VPVDNKRYRYAYHRSSWL------VAGKADPPLPARLYVHPDSPF---TGEQLLK---QM 200
                 :||...|...|:    |:      |..:.|....|:|.....:..   .|..:||   |:
  Fly  1673 QREHSIPVQRHRRSMAF----WVLQINGQVHFEIDTESTAKLAAQQKNAIGTPPGLNVLKIPSQL 1733

Human   201 -VSFEK--------VKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIF 256
             |..||        |.:.::|.|..|.           |..:|.::|...:..::|.|..||...
  Fly  1734 SVEIEKNQDEVPPVVVIDSDEEDDDGE-----------RQLVIDEQDDEQAETDVKQEVERTGFT 1787

Human   257 PETVFTAVTAYQNQLITKLKIDSNP--------FAKGFR-----------DSSRLTDIERESV-- 300
            .:|: .:..|.|..:....:..|:|        |:.||.           :::..|......|
  Fly  1788 IQTL-PSSGALQITISDSAETSSHPAKDVNTCHFSGGFMPFIANVPAKFGETAPTTQFLTPQVQV 1851

Human   301 -----------------------------ESLIQKHSYARSP----IRTYGGEEDVLGDES-QTT 331
                                         |||.:..|....|    |.....:|..|.:|: |..
  Fly  1852 TTSQSGPETLTSSSSSHLPASKSAYPKINESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVV 1916

Human   332 PNRGSAFTTSDNLSLSSWVSSSSSFPGFQ----HPQSLTALGTSTASIATPI------------- 379
            .|:.|...|..:..::...||:::....:    .|||     ||.:.:|.||
  Fly  1917 KNKKSIAITGIHKQVTKAASSTATVTAARAPVVKPQS-----TSVSKVAPPIRPGATTQPKTLVR 1976

Human   380 --PHPI----QGSLPPYSRLGMPLTPSAIASSMQG---------SGPTFPSFHMPRYHHYFQQGP 429
              |.|.    :.|||..::     ||.|.....|.         ||.|.|:...|.........|
  Fly  1977 LYPKPALAAGRKSLPANAK-----TPVATPRQSQPVACDKPPLVSGSTLPALVEPSARKSLPSKP 2036

Human   430 YAAIQGLR 437
            .||.:.||
  Fly  2037 LAAGEHLR 2044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX20	NP_001071121.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..81		5/48 (10%)
		T-box_TBX20-like	100..289	CDD:410319	45/244 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..340		6/24 (25%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<337..>409	CDD:476819	20/103 (19%)
ocm	NP_611894.1	MGA_dom	771..821	CDD:464998
		PRK12323	<1933..>2053	CDD:481241	29/122 (24%)