Protein Alignment PSMC5 and Rpt6

DIOPT Version :10

• Sequence 1: NP_002796.4
• Gene: PSMC5 / 5705
• HGNCID: 9552
• Length: 406
• Species: Homo sapiens
• Sequence 2: NP_608447.1
• Gene: Rpt6 / 33105
• FlyBaseID: FBgn0020369
• Length: 405
• Species: Drosophila melanogaster
• Alignment Length: 400
• Identity: 372/400 - (93%)
• Similarity: 386/400 - (96%)
• Gaps: 1/400 - (0%)

Human     8 QMELEEG-KAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGS 71
            :||:|.. ..|.|.|.||:.|||||||:|.:|.||||||||||||||||||:|||||||||||||
  Fly     6 RMEIESAYHKGEGFRSYYIQKIEELQLVVAEKHQNLRRLQAQRNELNAKVRMLREELQLLQEQGS 70

Human    72 YVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVS 136
            ||||||:.|||||||||||||||||||:|||||||||||||||||||:|||||||||||||||||
  Fly    71 YVGEVVKPMDKKKVLVKVHPEGKFVVDLDKNIDINDVTPNCRVALRNESYTLHKILPNKVDPLVS 135

Human   137 LMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLAR 201
            ||||||||||||||:||||||||||||||||||||||||:|||||||||||||||||||||||||
  Fly   136 LMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPELFDALGIAQPKGVLLYGPPGTGKTLLAR 200

Human   202 AVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGD 266
            ||||||:|||||||||||||||||||:||||||||||||||||||||||||||||||:|.|||||
  Fly   201 AVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSSRIESGSGGD 265

Human   267 SEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKI 331
            ||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||
  Fly   266 SEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPNEEARLDILKI 330

Human   332 HSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSE 396
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   331 HSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSE 395

Human   397 KNMSIKKLWK 406
            ||||||||||
  Fly   396 KNMSIKKLWK 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSMC5	NP_002796.4	PRK03992	24..400	CDD:179699	357/375 (95%)
		May mediate interaction with PRPF9. /evidence=ECO:0000250|UniProtKB:P62196	186..406		214/219 (98%)
Rpt6	NP_608447.1	PRK03992	23..399	CDD:179699	357/375 (95%)