Protein Alignment lrrtm1 and Fili

DIOPT Version :10

• Sequence 1: XP_005160139.1
• Gene: lrrtm1 / 570385
• ZFINID: ZDB-GENE-050506-80
• Length: 524
• Species: Danio rerio
• Sequence 2: NP_001369108.1
• Gene: Fili / 5740472
• FlyBaseID: FBgn0085397
• Length: 789
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 146/607 - (24%)
• Similarity: 231/607 - (38%)
• Gaps: 148/607 - (24%)

Zfish    14 WPLRKPPGLILCSLGIVLKIVPLVGGSCPRLCRC----DNKQLYCEGLNLTDIPQNLSSAIG--- 71
            |.....|.|:|..|.:|: :.|.....||..|:|    .|.:..|....|.|:|..|:....
  Fly    16 WLCGAIPVLLLLLLTLVI-LPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYIN 79

Zfish    72 ---------------------LSLRENNISELREGNFVGLSQLTWLYLDHNNIEIVEESAFERLR 115
                                 |.|.:|.|..|...||...|:|..|.|..|.:..:.:.||:.|.
  Fly    80 LTVNRIRTLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLT 144

Zfish   116 RIKELDLSTNRIESLPNGTFRPLPNLRILDLSYNRLQSLEPDLFHGLRKLTNLHLRYNALKFIPV 180
            .:..||||.||||::.......|.:|..|||:.|.:.|||.:.|.|:..|..|..|.|.|..:|.
  Fly   145 NLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPA 209

Zfish   181 RIFQDCRSMQFLDLGYNQLQSLARNSFAGLFKLTELHLEHNELVKVNLAHFPRLISLRTLYMRNN 245
            .......:::.||:..|.::.:..:||.||.:|..|.::.|.:.:::|:.|..||||:.|.:.:|
  Fly   210 SNLWHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDN 274

Zfish   246 KATIV-------VNTLEW----------------------------TWDYLEKID---------- 265
            ..|:|       ::.|.:                            ..|:|::||
  Fly   275 NLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHL 339

Zfish   266 ----FSNN-EIEYIEPHVFESVPKLNTLMLDSNKL--TYIDQRILDSWTSLSSITLSGNDWECSR 323
                .:|| ::..|...:|:..|.:..:.:.||.|  .|..|..:|   .|..:.|..|..:|:
  Fly   340 QTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVD---QLQKLYLGDNPLQCN- 400

Zfish   324 NVCALASWL-----SNFQG------QRDSGLLCANPDIAQGEDILDAVYAFQLCEDNVEA----- 372
              |:|. ||     .||:|      ....|.:.|....|..|::.|...|....:|.|.|
  Fly   401 --CSLL-WLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAYI 462

Zfish   373 ----------TT-----QTFTVTRNRPRGFIYEGPTKNPYDLQ----DMEGGEVVTNSLTVTASA 418
                      ||     :..|.:.||..|.:       ..|.|    |:...:|.|....:|.|.
  Fly   463 AEQHIVNALHTTEPSAYELATSSSNRNSGIL-------RMDRQQIGCDIWRDKVRTRRKLLTMSE 520

Zfish   419 DDLESTMKIHKVVTGTMALIFSFLIMVLMLYVSWKCFPAGVRQLRQCFTSQRRKQKQKQTMQQMA 483
            .::.....|..||...:..:...:|.:.:||           .||  |..:|||...::...:
  Fly   521 GEITCPAHIVTVVCAVITCLLVAMIGISVLY-----------YLR--FVKRRRKLLHERGPMR-- 570

Zfish   484 TTSASEYYVDYK--PNHIDGGL 503
             ||.|...|..:  ..|..|||
  Fly   571 -TSKSIINVHDRILQGHNPGGL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lrrtm1	XP_005160139.1	LRR	<50..355	CDD:443914	95/391 (24%)
		leucine-rich repeat	72..92	CDD:275380	7/19 (37%)
		leucine-rich repeat	93..116	CDD:275380	7/22 (32%)
		leucine-rich repeat	117..140	CDD:275380	9/22 (41%)
		leucine-rich repeat	141..164	CDD:275380	10/22 (45%)
		leucine-rich repeat	165..188	CDD:275380	6/22 (27%)
		leucine-rich repeat	189..212	CDD:275380	7/22 (32%)
		leucine-rich repeat	213..236	CDD:275380	6/22 (27%)
		leucine-rich repeat	237..259	CDD:275380	6/56 (11%)
		leucine-rich repeat	261..284	CDD:275380	7/37 (19%)
		leucine-rich repeat	285..305	CDD:275380	5/21 (24%)
Fili	NP_001369108.1	LRR	71..>348	CDD:443914	67/276 (24%)
		leucine-rich repeat	75..97	CDD:275378	0/21 (0%)
		leucine-rich repeat	98..121	CDD:275380	7/22 (32%)
		leucine-rich repeat	122..145	CDD:275380	7/22 (32%)
		leucine-rich repeat	146..169	CDD:275380	9/22 (41%)
		leucine-rich repeat	170..193	CDD:275380	10/22 (45%)
		leucine-rich repeat	194..217	CDD:275380	6/22 (27%)
		leucine-rich repeat	218..265	CDD:275380	13/46 (28%)
		leucine-rich repeat	266..289	CDD:275380	5/22 (23%)
		leucine-rich repeat	290..313	CDD:275380	1/22 (5%)
		leucine-rich repeat	314..338	CDD:275380	4/23 (17%)
		LRR_8	337..397	CDD:404697	14/62 (23%)
		leucine-rich repeat	339..360	CDD:275380	4/20 (20%)