Protein Alignment SLC17A7 and slc17a7

DIOPT Version :10

• Sequence 1: NP_064705.1
• Gene: SLC17A7 / 57030
• HGNCID: 16704
• Length: 560
• Species: Homo sapiens
• Sequence 2: NP_001072608.1
• Gene: slc17a7 / 780064
• XenbaseID: XB-GENE-5742677
• Length: 576
• Species: Xenopus tropicalis
• Alignment Length: 549
• Identity: 462/549 - (84%)
• Similarity: 507/549 - (92%)
• Gaps: 8/549 - (1%)

Human     1 MEFRQEEFRKLAGRALGKLHRLLEKRQEGAETLELSADGRPVTTQTRDPPVVDCTCFGLPRRYII 65
            ||||:|||:||||..||.|||:|||:|...||:||:.:||||..:.:..||||||||||||||||
 Frog     1 MEFRKEEFKKLAGNTLGHLHRILEKKQTNGETIELTEEGRPVIKEEKRQPVVDCTCFGLPRRYII 65

Human    66 AIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQKAQFSWDPETVGLIHGSFFWGYIVT 130
            ||||||||||||||||||||||||||||:|.::|..:|:::|||:|||||||:||||||||||||
 Frog    66 AIMSGLGFCISFGIRCNLGVAIVSMVNNNTVYKGNKIVIEQAQFTWDPETVGMIHGSFFWGYIVT 130

Human   131 QIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWS 195
            |||||:||||||||||||||||||||||||||||||||:.|||.|||||||||||||||||||||
 Frog   131 QIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACVICVRILQGLVEGVTYPACHGIWS 195

Human   196 KWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESP 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||.||:||:|||||||
 Frog   196 KWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGIMWYMFWILVSYESP 260

Human   261 ALHPSISEEERKYIEDAIGESAKLMNPLTKFSTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQ 325
            |:||:|||||:||||::||||..||||:.||..|||:||||||||||||||||||||||||||||
 Frog   261 AIHPTISEEEKKYIEESIGESTGLMNPMAKFKAPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQ 325

Human   326 PAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRRIMSTTNVRKLMNCGGFGMEAT 390
            |||||||||||||||||:|||||||||||||||||||||||::||||||||||:|||||||||||
 Frog   326 PAYFEEVFGFEISKVGLLSALPHLVMTIIVPIGGQIADFLRTKRIMSTTNVRKMMNCGGFGMEAT 390

Human   391 LLLVVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPII 455
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||:|
 Frog   391 LLLVVGYSHSRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLI 455

Human   456 VGAMTKHKTREEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKCGFVGHDQLAGSD 520
            ||||||||||||||||||||||||||||:|||:||||||||||||||.|:|||||:..|:||
 Frog   456 VGAMTKHKTREEWQYVFLIASLVHYGGVLFYGIFASGEKQPWAEPEETSDEKCGFIHEDELA--- 517

Human   521 DSEMEDEAEPPGAPPAPPPSYGATHSTFQ 549
             .|.|::::..||    ..|||||.:|.|
 Frog   518 -DESEEQSQAYGA----YGSYGATQTTSQ 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC17A7	NP_064705.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	384/423 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		26/53 (49%)
slc17a7	NP_001072608.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	384/423 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	517..547		12/33 (36%)