Protein Alignment CCNL1 and CycH

DIOPT Version :10

• Sequence 1: NP_064703.1
• Gene: CCNL1 / 57018
• HGNCID: 20569
• Length: 526
• Species: Homo sapiens
• Sequence 2: NP_524207.1
• Gene: CycH / 40429
• FlyBaseID: FBgn0022936
• Length: 324
• Species: Drosophila melanogaster
• Alignment Length: 243
• Identity: 56/243 - (23%)
• Similarity: 104/243 - (42%)
• Gaps: 52/243 - (21%)

Human    99 LPQVAMATGQVLFHRFFYSKSFVK-HSFEIVAMACINLASKIEEAPRRIRDVINVFHHLRQLRGK 162
            :|:..:.|....|.||:.:.|.:. |..||:| .|:.:|.|:||....|...:|      .::|.
  Fly    75 MPKCVVGTAFHYFKRFYLNNSPMDYHPKEILA-TCVFVACKVEEFNVSINQFVN------NIKGD 132

Human   163 RTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQTLVQTAWNY 227
            |..:..|           |:..|..::.:|.:.:.:.:|.:.|..:|         ..::|..|.
  Fly   133 RNKATDI-----------VLSNELLLIGQLNYYLTIHNPFRPIEGFL---------IDIKTRSNM 177

Human   228 MN-DSLRTNV--FV----------RFQPETIACACIYLAARALQIPLPTRPHWFLLFGTTEEEIQ 279
            .| |.||.::  |:          ...|..||.|.:..||...|..|.:.. ..|||.:..|::.
  Fly   178 QNPDRLRPHIDSFIDSTYYSDACLLHTPSQIALAAVLHAASREQENLDSYV-TDLLFVSAREKLP 241

Human   280 EI--CIETLRLYTR--KKPNYELLEKEVEKRKVALQEAKLKAKGLNPD 323
            .:  .:..:|:..:  ::|:.|.: |.:||:   |.:.:.:|.  |||
  Fly   242 GLIDAVRKIRIMVKQYQQPDREKV-KAIEKK---LDKCRNQAN--NPD 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNL1	NP_064703.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		CYCLIN_SF	40..195	CDD:477360	23/96 (24%)
		Cyclin-like 1	88..190		22/91 (24%)
		CYCLIN_SF	199..321	CDD:477360	30/138 (22%)
		Cyclin-like 2	203..287		21/98 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..526		3/6 (50%)
		RS	390..432
CycH	NP_524207.1	ccl1	2..307	CDD:129660	56/243 (23%)