Protein Alignment CCNL1 and CG16903

DIOPT Version :10

• Sequence 1: NP_064703.1
• Gene: CCNL1 / 57018
• HGNCID: 20569
• Length: 526
• Species: Homo sapiens
• Sequence 2: NP_569980.1
• Gene: CG16903 / 31178
• FlyBaseID: FBgn0040394
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 258/557 - (46%)
• Similarity: 325/557 - (58%)
• Gaps: 85/557 - (15%)

Human     7 STATAAAAASSAAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHSLIPEERLSPTPSMQ 71
            |...:::.|:..|.:|||.:.|...........|.  .||::.:.||:::|||||.::..|||.|
  Fly    41 SNNNSSSGAAPGADAAGGDAGGVAAAQADANKPIY--PRLFNRIVLTLENSLIPEGKIDVTPSSQ 103

Human    72 DGLDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLA 136
            ||||..:|.|||||||||||.|||||||||||||||||||.|||||||||:|:.|.|||:|:.||
  Fly   104 DGLDHETEKDLRILGCELIQTAGILLRLPQVAMATGQVLFQRFFYSKSFVRHNMETVAMSCVCLA 168

Human   137 SKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELGFCVHVKHP 201
            |||||||||||||||||||::|:|.::..||::||..|.|.|.||||||||||||||||||||||
  Fly   169 SKIEEAPRRIRDVINVFHHIKQVRAQKEISPMVLDPYYTNLKMQVIKAERRVLKELGFCVHVKHP 233

Human   202 HKIIVMYLQVLECERNQTLVQTAWNYMNDSLRTNVFVRFQPETIACACIYLAARALQIPLPTRPH 266
            ||:||||||||:.|:::.|:|.:||:|||||||:||:|:.||.||||||||:||.|.||||..|.
  Fly   234 HKLIVMYLQVLQYEKHEKLMQLSWNFMNDSLRTDVFMRYTPEAIACACIYLSARKLNIPLPNSPP 298

Human   267 WFLLFGTTEEEIQEICIETLRLYTRKKPNYELLEKEVEKRKVALQEAKLKAKGLNPDGTPALSTL 331
            ||.:|.....:|.:||...:.||.|.||..|.||..|::.|....:|:.|.|..|.  .||:.|:
  Fly   299 WFGIFRVPMADITDICYRVMELYMRSKPVVEKLEAAVDELKKRYIDARNKTKEANT--PPAVITV 361

Human   332 ----------GGF----SPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKD 382
                      |||    .|...||        ||||                          :||
  Fly   362 DRNNGSHNAWGGFIQRAIPLPLPS--------EKSP--------------------------QKD 392

Human   383 SKRSRNSRSASRSRSRT-RSRS-RSHTPRRHYNNRRSRSGTYSSRSRS------RSRSHSESPRR 439
            | ||| |||.:|:.||| |||| ||.:|.|....:..||.:..|||||      :||.:|.||.|
  Fly   393 S-RSR-SRSRTRTHSRTPRSRSPRSRSPSRERTKKTHRSRSSRSRSRSPPKHKKKSRHYSRSPTR 455

Human   440 HHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRS 504
            .::..|.|.|:|.:|:      |..:..||.||.:...|.:..|..|.........:..|..|.|
  Fly   456 SNSPHSKHRKSKSSRE------RSEYYSKKDRSGNPGSSNNLGDGDKYRNSVSNSGKHSRYSSSS 514

Human   505 FERSHKSKHHG----------------GSRSGHGRHR 525
            ..|:......|                |||.|| :||
  Fly   515 SRRNSGGGGDGRSGGGGGGGGGGNGNHGSRGGH-KHR 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNL1	NP_064703.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		7/28 (25%)
		CYCLIN_SF	40..195	CDD:477360	108/154 (70%)
		Cyclin-like 1	88..190		77/101 (76%)
		CYCLIN_SF	199..321	CDD:477360	65/121 (54%)
		Cyclin-like 2	203..287		48/83 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..526		74/246 (30%)
		RS	390..432		22/49 (45%)
CG16903	NP_569980.1	CYCLIN_CCNL1_rpt1	104..227	CDD:410292	94/122 (77%)
		CYCLIN_CCNL_rpt2	232..323	CDD:410236	53/90 (59%)
		SDP_N	<440..>482	CDD:463517	14/47 (30%)