Protein Alignment PSMC1 and rpt-2

DIOPT Version :10

• Sequence 1: NP_002793.2
• Gene: PSMC1 / 5700
• HGNCID: 9547
• Length: 440
• Species: Homo sapiens
• Sequence 2: NP_504558.1
• Gene: rpt-2 / 178988
• WormBaseID: WBGene00004502
• Length: 443
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 368/443 - (83%)
• Similarity: 411/443 - (92%)
• Gaps: 3/443 - (0%)

Human     1 MGQSQSGGHGPG---GGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKL 62
            |||.|||..|.|   |....:|.:|||||.|:|:|:|||||.:||||||||||.||||.:|||||
 Worm     1 MGQQQSGFGGRGNDRGAGDGEKKEKKKYEAPIPSRIGKKKKGSKGPDAASKLPAVTPHARCRLKL 65

Human    63 LKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSV 127
            ||.||||||||||:|||:|||::||.||:|||||:|||:||||||:||:|||||||.||||||:|
 Worm    66 LKSERIKDYLLMEQEFIQNQERLKPQEERQEEERAKVDELRGTPMAVGSLEEIIDDQHAIVSTNV 130

Human   128 GSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDN 192
            ||||||:|:|||||:.||||||||||||.|||||||.|||||:|:|||:||||||||||:||||.
 Worm   131 GSEHYVNIMSFVDKEQLEPGCSVLLNHKNHAVIGVLSDDTDPMVSVMKLEKAPQETYADVGGLDQ 195

Human   193 QIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQ 257
            |||||||:||||||||||||||||:|||||||||.||||||||||||||||||||||:|||||||
 Worm   196 QIQEIKEAVELPLTHPEYYEEMGIRPPKGVILYGCPGTGKTLLAKAVANQTSATFLRIVGSELIQ 260

Human   258 KYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSR 322
            ||||||||:||||||||||:||||||||||||:||||||||||||||||||||||||||||||||
 Worm   261 KYLGDGPKMVRELFRVAEENAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSR 325

Human   323 GDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAK 387
            |||||:|||||||:|||||||||||||||||||||||||:||||||||||||..:|.|::.|.||
 Worm   326 GDVKVLMATNRIESLDPALIRPGRIDRKIEFPLPDEKTKRRIFQIHTSRMTLGKEVNLEEFITAK 390

Human   388 DDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440
            |:||||||||:||||||:|||||||:||.|||:||||||||:|:||.||.|||
 Worm   391 DELSGADIKAMCTEAGLLALRERRMRVTMEDFQKSKENVLYRKKEGAPEELYL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSMC1	NP_002793.2	PTZ00361	1..440	CDD:185575	366/441 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		30/50 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	84..104		13/19 (68%)
rpt-2	NP_504558.1	PTZ00361	1..443	CDD:185575	366/441 (83%)