Protein Alignment LHX9 and Lmx1a

DIOPT Version :10

• Sequence 1: XP_011508083.2
• Gene: LHX9 / 56956
• HGNCID: 14222
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_729801.1
• Gene: Lmx1a / 39406
• FlyBaseID: FBgn0052105
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 301
• Identity: 95/301 - (31%)
• Similarity: 130/301 - (43%)
• Gaps: 63/301 - (20%)

Human    76 LCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCA 140
            ||.|||.||.||:.:...|..||.:||.||.|.:.|..  ||:.::..:|||.||.|.|.| :|:
  Fly   274 LCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHH--TCYVRNSKLYCKMDYDRLFGV-KCS 335

Human   141 RCHLGISASEMVMR-ARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGEYPPQ 204
            .|...|...|:||| ..:.|:||.||.|..|...|..|:.|.::|..::|..|       :...:
  Fly   336 SCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRH-------DLEKE 393

Human   205 LSYTELAAKSGGLALPYFNGTGTVQKGRPRK-RKSPALGVDIVNYNSGCNENEADHLDRDQQPYP 268
            :.....||:..|     |.|.......|||. |:.|
  Fly   394 MFLAAAAAQHCG-----FVGLDEEDLLRPRDGRRGP----------------------------- 424

Human   269 PSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR-NL 332
                 ||.||.....|.:..|:.|..:..|..|..:.||:.|||:.||:||||||.|||.:: ..
  Fly   425 -----KRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQR 484

Human   333 LRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTN 373
            ..::|||.....|          ||..|...:||...| ||
  Fly   485 KAKQNGGSGGGSG----------SGRGTGNSSATDDKD-TN 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LHX9	XP_011508083.2	LIM1_Lhx2	67..130	CDD:188853	23/53 (43%)
		LIM2_Lhx2_Lhx9	135..193	CDD:188763	20/58 (34%)
		Homeodomain	274..330	CDD:459649	25/55 (45%)
Lmx1a	NP_729801.1	LIM1_Lmx1b	275..327	CDD:188757	23/53 (43%)
		LIM	333..388	CDD:413332	19/54 (35%)
		Homeodomain	425..481	CDD:459649	25/55 (45%)