Protein Alignment chd7 and kis

DIOPT Version :9

• Sequence 1: XP_697956.4
• Gene: chd7 / 569471
• ZFINID: ZDB-GENE-070912-179
• Length: 3140
• Species: Danio rerio
• Sequence 2: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Alignment Length: 4673
• Identity: 1294/4673 - (27%)
• Similarity: 1792/4673 - (38%)
• Gaps: 1799/4673 - (38%)

Zfish    23 GLGDCGYPQ------GQTNPMS-QQMPHEHQGYGQLPPSLHLSSPAVPGQAKLGHHFDPFNQYEQ 80
            ||....||.      |...|.| ||...:||.:|....:.||:  |:..|           |.:|
  Fly   511 GLPPMDYPSAYRSAVGPRMPASPQQQQQQHQQWGAAHGAQHLA--ALQQQ-----------QAQQ 562

Zfish    81 PKMHPMDQQGGRMMGNGPVNGMSSPHSRYHGAQAGAGGAAGHHVYPGAQGDGRSQSFPDSGNTWG 145
            .:.....||            .:.|..:...|...|  ...||          .|.....|...|
  Fly   563 QQQQVQQQQ------------QAPPQQQQQAAMLQA--QQQHH----------QQQLSMYGQPMG 603

Zfish   146 AQPMQVPEQTRPPFQQQPP--------QASSHQHGPAGPQGHAHQMGPFIGRGDY--AIQG-HNQ 199
            .||....:|..||...|||        |...||......| ..|.:...:|.|:.  |..| .||
  Fly   604 QQPQTAQQQVVPPVTSQPPVVAASQQQQQQQHQQQSLNDQ-LQHSINDIVGGGNSSGATGGAQNQ 667

Zfish   200 TQTPPRMNHFPQGLPQEANHFLGHVGMTQNPGMSGPPIRHLAQPSQQHQQPNQQFLHRPGQGPVH 264
            .|..|::......|.|:                :.|.:.||.||:.:..||.||         ..
  Fly   668 HQQQPQLAAMSSPLHQQ----------------NLPNMHHLIQPTMETTQPTQQ---------QQ 707

Zfish   265 PDSVASHNPQFPQ----SPSRQQQQQQQVMGGRPHQNMGFNMHNQQVPSNTVNSSGQYPPYSSYG 325
            ..|.....||.||    ||..||.|.|..:    ||......|.|.:||.. .|..|:.|:::..
  Fly   708 QTSQQQQQPQQPQATLTSPHHQQMQHQSPI----HQQQQSPHHQQHLPSYN-QSQQQFDPFANIL 767

Zfish   326 NLNQGLANTSGMSPNLSLTTSSNSNPNAPVTQVQRYPAPAGPQRYPTPGGQQGPLHQQPIHVNQI 390
            ..||..|:...|||         ::.::||      ||....|::.|   ||.|..|.|....|.
  Fly   768 GDNQPAASQQTMSP---------AHVSSPV------PAQMQQQQHQT---QQQPSQQVPQSQQQQ 814

Zfish   391 NTQPMHPAQNQATAQPKLQQHLPPPPQGSYSSPPSMSPMRNLATPAGTPPPQQVRPPSAGLATD- 454
            .:||....|.|..:.|  ..||......:.:|..|.:    ||..|     ......|:..:|:
  Fly   815 VSQPQQQTQQQQPSTP--SHHLSSILNETANSNDSST----LAVAA-----NDSNNSSSNSSTNS 868

Zfish   455 -VGGYPGVPHQSQGPMAHAQRGAGPMNAAQPLPHQQLPSHSTHPHPPTTQMYA------------ 506
             |...|...|.|     ::|......:..|    |||...:|:.|...::...
  Fly   869 IVNNQPTSVHDS-----NSQSSINSSSNNQ----QQLLMDNTNSHGGNSESAQNAGVDVGLFDNN 924

Zfish   507 ALSPNHRATAAQGRSSTTPGG----------------NHTEPPG--------------PQDQ--- 538
            ::|.|..|.||...::.:...                |.:|..|              |||:
  Fly   925 SMSSNSAAVAAVASNAASAAAALLDSNSQSSNAEFEKNQSEGEGLGVVEGVIANETDLPQDENSV 989

Zfish   539 ----------RLHAQQAQCQQLQKPPLPFQQQQLQQ---------VHTPPSI------------- 571
                      .|...|...|  :||....:|.||.|         :..|.::
  Fly   990 SKTQDITLSTELPTIQDDLQ--EKPTAEMEQTQLGQSLGDLSKSLLEEPKTVEESGEDKSQSAPG 1052

Zfish   572 --PPSQTHLAAHHQSSPPSQ------------------QAWAPTHQSP--PPMQKVP------HM 608
              ||:...:..   :.||.|                  ||....|..|  ||....|      .|
  Fly  1053 VAPPADPIIPV---TQPPQQQMPPIGMPMHPIAPGYEAQAQGQGHMPPMMPPYGGAPGMYPPYPM 1114

Zfish   609 LHS----------------PPDPSLE------------------------------IITSSKTPA 627
            ||.                ||...|:                              ::..:..|.
  Fly  1115 LHQQEIAALQQQIQELYCMPPGHELQHQDKLMRMQERLNLLTQHEVNDQCAGGPQCLLFQNVPPM 1179

Zfish   628 MGPNLQPANCDLQQKESE-------------------LKPKKKKKKKAKVSEGQECNNIS----- 668
            .||   |.|..|.|:..|                   .||:.||.:||:|.:.|:..:||
  Fly  1180 YGP---PGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPRAKKGEKAQVGQQQDLMDISGNVAM 1241

Zfish   669 ------------------------------------SEAGGEVTALMNEGDSLITPVEKPAEKKS 697
                                                ||..|:::..::..:.|.|..:...:||.
  Fly  1242 GAANAVSSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKK 1306

Zfish   698 KKKPKEKEPKEPKEPKTPKTPKTPKTPKEPKEPKEKKVKTATPK--------------------- 741
            .:||  :.||:|.:|...:|||. |.||:|.:|...:...|..|
  Fly  1307 PRKP--RTPKDPNKPPRDRTPKA-KKPKDPNDPNSTETPAAVKKRAGASKRRKQYGEDGAEQTGE 1368

Zfish   742 -----------PKS----------------------------SKKP------------------- 748
                       ||:                            ||.|
  Fly  1369 GSEVEDNKPLVPKAGSADGEAETTSGGTGVDGESPDYDDIPVSKIPRGSNEDEKEAEAGDETVDS 1433

Zfish   749 -----------------------SAKKSDSESGNSTKKE---------AKRKREPSVTSD----- 776
                                   |.:.::||.|.|.:|.         .||:....:..:
  Fly  1434 VPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLSAKALKKRRNRGRIVPESDGED 1498

Zfish   777 --VEKTPPQSPEEEDDDGVQKRRSSRQVKRKRYTEDLEFRISDDDDGDDSAGP----KSPTTS-- 833
              :::|||.||..:.:....||||||..:||:|.:|:..|.|||::....|.|    |.|:.:
  Fly  1499 DTLDRTPPPSPPPDSEMDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANAS 1563

Zfish   834 ---------------------------EQQELP-------------------------------- 839
                                       |:..||
  Fly  1564 NSNAGSDVEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAM 1628

Zfish   840 ------------DAEGPVVEKIMGMRMGKKEL--------------------------------- 859
                        |.:..||:.::.|||||:||
  Fly  1629 SSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDE 1693

Zfish   860 ----------------------------------------------------------------- 859
                                                                             
  Fly  1694 KFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKDKMEVDDEVGKSDKESK 1758

Zfish   860 ----------------------------------------------------------------- 859
                                                                             
  Fly  1759 PEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKST 1823

Zfish   860 --------------------------ASGEE----------------------IEVEEFYVKFKG 876
                                      ..|||                      |:|||::||::.
  Fly  1824 DDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRN 1888

Zfish   877 FSYLHCRWADIEELEK-DKRIQQKIKRFRAKQALSTFVTE-MDDEPFNPDYVEVDRVLDVSESTD 939
            ||||||.|...|||.| |:|:..||:||:.||:....:.| ::|||||.|:.|||||||:|..||
  Fly  1889 FSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTD 1953

Zfish   940 E-NGELVTLYLVKWCSLPYEDSTWELKADIDQVKIEEFERV--MAREPQLKRVERPPTSDWQKSE 1001
            | :||....|||||.||||||.||||:.|:|..|||::.|.  :.:..:.|..:||....|:|.|
  Fly  1954 ETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWKSKKRPHPELWKKLE 2018

Zfish  1002 SSREYKNANALREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVI 1066
            .:..||..|:||.|||||:|||.|:||||.||||||||||||||||:||::.:|..||.||||||
  Fly  2019 KTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVI 2083

Zfish  1067 APLSTIPNWEREFRTWTELNVVVYHGSQASRKTIQAYEMYYRDTQGRIIKGAYKFHAVITTFEMI 1131
            |||||||||:|||..||::||||||||..|::.||.||.||:...|:::|...||:.:|||||||
  Fly  2084 APLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMI 2148

Zfish  1132 LTDCPELRNVPWRCVIIDEAHRLKNRNCKLLEGLKMMDMEHKVLLTGTPLQNTVEELFSLLNFLE 1196
            :||..:|:...||..:||||||||||||||||||:.:::||:|||:||||||.:.||||||||||
  Fly  2149 VTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLE 2213

Zfish  1197 PDRFPSESTFMQEFGDLKTEEQVQKLQGILKPMMLRRLKEDVEKNLAPKEETIIEVELTNVQKKY 1261
            |.:|.|:..||.|||.|:|||:|.|||.:||||||||||:||||:|||||||||||||||:||||
  Fly  2214 PSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKY 2278

Zfish  1262 YRAILEKNFAFLSKSGAGGGSGGGGGSNVPNLLNTMMELRKCCNHPYLINGAEEKIMEEFRETHP 1326
            ||.|||:||:||.|        |...:|:|||:||||||||||.||||:|||||:|..:|:..|.
  Fly  2279 YRGILEQNFSFLKK--------GTTSANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHG 2335

Zfish  1327 LDQPEFHLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGR 1391
            .| ||.:.:.:|.:|||:||||||||||||.|||||||||||||||||||||:.|:||:||||||
  Fly  2336 ED-PESYYKNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGR 2399

Zfish  1392 VRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIG 1456
            :||||||.||||:|:|.||||||||||:|||||||||||||.||:||||||||||||||||||||
  Fly  2400 IRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIG 2464

Zfish  1457 QSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENAANGVQQLSKKEIEDLLRKGAY 1521
            |.|.||||||:.||:||||||||||:||||||||||||:.:.:.....:|||||||||||:||||
  Fly  2465 QRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAY 2529

Zfish  1522 GALMEEEDEGSKFCEEDIDQILQRRTQTITIESEGKGSTFAKASFVSAGNRTDISLEDPDFWQKW 1586
            ||:|::::.|.||||||||.||:||||.||:||| |||||:||||.::|||:||:::|||||.||
  Fly  2530 GAVMDDDNAGDKFCEEDIDSILKRRTQVITMESE-KGSTFSKASFAASGNRSDITIDDPDFWTKW 2593

Zfish  1587 AKKAELDLDAI--NGRNNLVIDTPRVRKQTRHYSSMKEDDLMEYSELESDSEDKP------IQKP 1643
            |||.::|.||.  :...:||:..||.|.|.:.|.   .:|:||.:..||.:|:..      ::..
  Fly  2594 AKKVDIDPDACERDETEDLVLSEPRRRTQIKRYG---HEDVMELNSEESSNENSDEEGGIGLRSR 2655

Zfish  1644 RRPQDRTQ-----------------------------GYPRSECFRVEKNLLVYGWGRWGDILSH 1679
            ||.:.|.:                             .:.:||||:|||.||.:|||||.::|..
  Fly  2656 RRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLEL 2720

Zfish  1680 GRFKRPLRERDVETICRALLAYCLLHYRGDENIKGFIWDLITPTEDGQSRTLT-NHSGLSAPVPR 1743
            |:|||..|:.|||...|.:|.|||..|:|||.||.||||||||||||:.:.:: :||||...|||
  Fly  2721 GQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPR 2785

Zfish  1744 GRKGKKGKLPVAQTRMPQADWLADCN--------------------------------------- 1769
            ||.|.|..........|.....:..|
  Fly  2786 GRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPN 2850

Zfish  1770 ---------PDLLLQEDSYKRHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGTDSSELDIWI 1825
                     .|..| |.:||:||..|.||||||||||||::.|||||...:|.:.|..|||.| .
  Fly  2851 HWSKKEKYDADAYL-EGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISELPI-R 2913

Zfish  1826 PQPFHADVPTDWWD-LDADKSLLIGVFKHGYEKYNSMRADPTLCFLERVG------------MP- 1876
            |.|....||:.||: :..|||||:|.:|||.|.|..|||||.|||:..||            :|
  Fly  2914 PPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPI 2978

Zfish  1877 -DAKAIAAEQRGADMMADGVE------------GEEEDPEYKPLR-------------------- 1908
             :..|.:....|.::..||..            |:.:|....|.|
  Fly  2979 NEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENASGGNDKTE 3043

Zfish  1909 ----------MSFK--------DDLD---------------DFTNSPLDDNND------------ 1928
                      .|:|        .|||               ..|:.|..:.||
  Fly  3044 SENDATTVSESSYKSEVLPGKGSDLDVSVAQQDALSATPELANTSDPKMNKNDAQVSASVSCDPA 3108

Zfish  1929 ------------------GMDGE-----------------TGEAPKL------------------ 1940
                              |..||                 ||:||.:
  Fly  3109 DSSSPEAAGKAQGTGVQTGDAGELDIESEKKDNEKETKESTGDAPAVEAKKDSAAIARAEGDKTE 3173

Zfish  1941 ---------------------------GENGKPGN------------------------------ 1948
                                       ..:.|..|
  Fly  3174 SCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTV 3238

Zfish  1949 -------LYWPPASALTARLRRLITAYQRTHKREQLRQEAMAK----------------PDRRRR 1990
                   ..||....|..||||:||||||.:|:|:|:.:..||                |..:..
  Fly  3239 AAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSM 3303

Zfish  1991 R-----------------------PRDDILAMVTEGGAYVPDGAVAFMADGGAFMAKGS------ 2026
            :                       .|.....|.::|.:.....|.|..:.||:....|.
  Fly  3304 QMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGA 3368

Zfish  2027 ---PFIPDSAAL--------------LAD-----SAAYF-----------------KERR----- 2047
               |.:|.:|.:              ||:     .|.|.                 |||.
  Fly  3369 GVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQ 3433

Zfish  2048 ---QRWTRREEADFYRVVSTFGVVYDVH-----------RQCFDWSQFRAFARLDKKTDESLEKY 2098
               ::|.||||.:|.||::.:||  |:|           ....||::|:..|.|::|:||:|..|
  Fly  3434 LIPKKWNRREEYEFLRVLTGYGV--DLHVSTPMASSNGSSLSPDWTKFKQMAHLERKSDETLTDY 3496

Zfish  2099 YCSFVAMCKRVCRMPL-KSETELPDPTIIIDPITEERASRTLYRIELLRRIREQVLPHPLLEERL 2162
            |..|||||||...:.| :||..|..   ||:.|.:|.|...|.|:|:|.::|| |..:|:|||||
  Fly  3497 YKVFVAMCKRQAGLKLSESERGLEG---IIEEIEKEHAKLILDRLEVLAKLRE-VARNPMLEERL 3557

Zfish  2163 SLCQPSPDLPAWWEPGRHDRDLLRGAAKHGVSRTDYHILNDPELSFLEAYRKFTQ---------- 2217
            .||..:.|.|.||||||||::|:....|||:.|::..|.|||..||.|:.::|.:
  Fly  3558 KLCTKNADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTI 3622

Zfish  2218 -------GKGVELPVIVSDPLT---------------------------------------PLTL 2236
                   .|..:|.....|..|                                       |:|
  Fly  3623 KLEAFNAEKAEKLAAAEKDAATEKAAATEKAAAEKAASVKNEVIDLDDELMTNESVIKKESPVT- 3686

Zfish  2237 PKDEEVKEEQGDVTLPKVENGSIEDVKEEKSEALSPKKEVKNEEDEN------------------ 2283
            |..||:|.|:..      |.....|..|:|:.......::|.:||.|
  Fly  3687 PIKEEIKSEESP------EKHDTADNLEDKNSDAEESTKIKGKEDFNPETTEKEALDESTNLNKD 3745

Zfish  2284 -----GLGPKQE---PKEEKMEVEEKDVTE--FKTDVEQVCPVDGMVEKKPMDQEPTD-TLPSSE 2337
                 .|.|:.|   |.|:||||||..|.|  .|....:.|  ....:||..:::|:. .:|..:
  Fly  3746 KSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEGSPEKC--SDAEDKKFSEEKPSSPAVPDGK 3808

Zfish  2338 ------DKNAQDEKELPTGNKLSTEKASEDE-----------------EEKMDEDDKSEKSS-QA 2378
                  |:.|.:.:|..:|:..|.||..||:                 ||:.:|.:|.|||| ::
  Fly  3809 VSEMEADEAAPNTEENCSGDSESPEKECEDKVVEKVEEEKGENSYEKAEEQKEETEKLEKSSIES 3873

Zfish  2379 EVGALSE----------RKN---------------------FDEESNASLSTARDETNETRDCF- 2411
            |....||          :|:                     ..|:..|.....:.:..|.:..|
  Fly  3874 EPSEKSETVLEPEVAVPKKSTGDQDILDLVAGPSDPDDDEVMKEKEKAVEEECKKQAAELKARFP 3938

Zfish  2412 SVDDVEP-SASQMFSERSLFSF----WPKDRVMINRMDNICEAVMKGKWPSNRRQFFDFPGLLPG 2471
            .::.::| :..|...|:.....    |.||..:..|:.:|...|..|.||.:.:
  Fly  3939 DLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGNWPVDSK----------- 3992

Zfish  2472 YSSMAT-----------------ESPLQRRSLG----------------DLSLVGQTSYSGSEDL 2503
            ||:.||                 .|.|:|||..                ..|.:.|.:.|.|...
  Fly  3993 YSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAAS 4057

Zfish  2504 TMS--PQVNKD-----------DALS--------------------------------------- 2516
            |.|  |||.:.           ||.|
  Fly  4058 TSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAG 4122

Zfish  2517 ----LSVPR------QRRRRRRKIEIEAERAAKRRNLMEM--------------VAQLRESHAEG 2557
                ||||.      ::|:|...|::|.|| ||...|:..              :..|..|...|
  Fly  4123 GVSGLSVPSAGSGVGKKRKRHIAIDVETER-AKLHALLNSSTMAPKDWESEIANMEALSGSSGRG 4186

Zfish  2558 QAQAIDLTKAL-------HSVSSSSSASAF-----------PGAMASSATLKAQM------ELLQ 2598
            :......:..:       |:..|..|:..|           |.:|.:...|.:.:      |:|:
  Fly  4187 RGGNSSASSGMQPPPAHQHASLSRQSSGQFSKPAVPAMKTPPPSMGAPMDLSSSLPKMNMTEMLK 4251

Zfish  2599 PGASS----------------------------RPRANGSLLDTELPNRRKR----------GRR 2625
            ..:||                            ....|.|.||..|....|:          |:.
  Fly  4252 SASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNKSKLDDTLNKLMKKNNCTIEEPVIGKE 4316

Zfish  2626 KNVEGLELLFMG-----------------NKRGQL-------------SAELSDGTKAF------ 2654
            |..:.|:.:.:|                 :|:.|:             |:......|.|
  Fly  4317 KKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSNQQSNQKPFTITVTT 4381

Zfish  2655 VDGR-----------THLAMPSPAQKASGEGLDEGSLQGEDGSSTKD-LREWLRQHPTYTMDMPG 2707
            |.|:           |..:..:....|.|.||.........|.|:|| |...|.|  |...|...
  Fly  4382 VPGKSKSGSSNSGSGTGGSSSASGGGAGGSGLSALQNMAMGGLSSKDSLNALLAQ--TMATDPQT 4444

Zfish  2708 YVPKNEDLLLSQFAKPKQK------------------RHRCRNPNKIDIN--------------- 2739
            ::.:.:.::  ||..|.|:                  :....:|:.:.:|
  Fly  4445 FLKQQQKMM--QFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDMTSPLGDQLS 4507

Zfish  2740 -----------------------------------------------------------TLTGEE 2745
                                                                       .|||||
  Fly  4508 IDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQQQHSMPGPQNLTGEE 4572

Zfish  2746 RVPVVNIRNGRKMGGAMAPPMKDLPRWLVENPEYAIAPDWTDIVKQSGFLPESMFDRLLTGPVVR 2810
            .|||:|.:.|:::||..||.:|.|.:||.|||.|.:.|.|.:.::.....|...       |...
  Fly  4573 PVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSTPSPR-------PASM 4630

Zfish  2811 EEG-----VRRRGRRPKAEIA---------KATAAAQAAA---------------AAAAA----- 2841
            |.|     |:..|.||.:.::         :.::|||:.|               ||:||
  Fly  4631 ESGYGSSAVKSHGGRPLSNLSSTSSSSHTQQQSSAAQSQAGGNSGSSKKNSRQQTAASAALDQAA 4695

Zfish  2842 ---ATTSGVNPLLMNGL-------------------------FGSM-DLTSLQGLQNLQSLQLAA 2877
               .:.:|:||.|:..|                         ||.| .:.::.||.||.::.|.|
  Fly  4696 LQFGSLAGLNPSLLANLPGLGAFDPKNPLAAFDPKNPLLSMSFGGMPGMGNIPGLGNLNNMNLFA 4760

Zfish  2878 GLMGFPTALGG-----GADAKHAAAMLPLMLPGMGGLPNMFSLGSLFGGNLAAAATATNGA-SST 2936
            .|.|    :||     |.|.:..||::....|.:|||..                 |:.|| |..
  Fly  4761 SLAG----MGGLGNLAGMDTQSLAALMAAAGPTLGGLTG-----------------ASGGAGSGK 4804

Zfish  2937 EQAESEENSKPKTDEETKGEGDEKEEKQAEKSSETVE---SADATGDAAALNAAAAAAAAGMSTG 2998
            .||:|:.::...:...:| :..:::::||:..:..:.   ||...|..|:....|||:|:.::.|
  Fly  4805 SQAQSQSSATSSSSSASK-KKQQQQQQQAQNEAAQLAAAISASTGGSGASGGKNAAASASQLAAG 4868

Zfish  2999 TLAFNPFLLSTMAPGLFYPSMFL----PPSLGGLAIPGFPQASLADLQSAVSGALGATGEDKESD 3059
            .    |||...  |.|.||.|.|    |.|||...: |.....||...:.::||
  Fly  4869 F----PFLFPN--PSLLYPPMGLGGLNPYSLGSSGL-GSAYDQLAQQYNLLNGA----------- 4915

Zfish  3060 KGPRTNQDPNASVADVETADNTLEDSDSEESQNKTADSSVLDDDLAGPAEEMDSMEGG 3117
                     .:|.::..:..:....|.|:.||::...:|.  :..|.....|.||.||
  Fly  4916 ---------TSSASNTSSTQSKSHQSQSKSSQSRNTTASA--NSAASLMNAMASMGGG 4962

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chd7	XP_697956.4	Pro-rich	322..491	CDD:291893	40/170 (24%)
		CHROMO	845..906	CDD:237991	35/272 (13%)
		Chromo	927..978	CDD:278797	33/51 (65%)
		SNF2_N	1015..1310	CDD:278600	201/294 (68%)
		DEXDc	1031..1180	CDD:238005	96/148 (65%)
		Helicase_C	1342..1456	CDD:278689	99/113 (88%)
		BRK	2742..2786	CDD:197800	22/43 (51%)
kis	NP_001137761.1	BASP1	1554..1786	CDD:283191	15/231 (6%)
		HepA	1676..2527	CDD:223627	439/859 (51%)
		SDA1	<1693..>1854	CDD:283052	1/160 (1%)
		CHROMO	<1879..1919	CDD:237991	22/39 (56%)
		Chromo	1941..1996	CDD:278797	34/54 (63%)
		DEXDc	2048..2197	CDD:238005	96/148 (65%)
		Helicase_C	2350..2464	CDD:278689	99/113 (88%)
		RR_TM4-6	3728..>3877	CDD:283990	37/150 (25%)
		BRK	4569..4613	CDD:197800	22/43 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	594	1.000	Domainoid score	I195
eggNOG	1	0.900	-	-		E2759_KOG0384
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1569	1.000	Inparanoid score	I83
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001075
OrthoInspector	1	1.000	-	-		otm24668
orthoMCL	1	0.900	-	-		OOG6_100621
Panther	1	1.100	-	-	LDO	PTHR45623
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3575
SonicParanoid	1	1.000	-	-		X648
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.850