Protein Alignment MRPS22 and MRPS35

DIOPT Version :10

• Sequence 1: NP_064576.1
• Gene: MRPS22 / 56945
• HGNCID: 14508
• Length: 360
• Species: Homo sapiens
• Sequence 2: NP_011681.1
• Gene: MRPS35 / 853075
• SGDID: S000003397
• Length: 345
• Species: Saccharomyces cerevisiae
• Alignment Length: 201
• Identity: 45/201 - (22%)
• Similarity: 74/201 - (36%)
• Gaps: 60/201 - (29%)

Human    63 PETKKPTFMDEEVQSILTKMTGLNLQKTFKPAIQELKP------PTYKL---MTQAQLEEATRQA 118
            |.||||..:..:.......:....||..||..:.:..|      ..|.|   :.|:..||.|.:.
Yeast   101 PVTKKPLQLRYDGTLGPPPVENKRLQNIFKDRLLQPFPSNPHCKTNYVLSPQLKQSIFEEITVEG 165

Human   119 VEAAKVR----LKMPPV--LEERVPI-------NDVLAEDKILEGTETTKYVF----TDISYS-- 164
            :.|.:|.    ||:|.|  :.:.|.:       |.|.::.|.::  ||...:|    :|.|:.
Yeast   166 LSAQQVSQKYGLKIPRVEAIVKLVSVENSWNRRNRVSSDLKTMD--ETLYRMFPVFDSDASFKRE 228

Human   165 ------IPHR---ERFIVV--REPSGTLRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTM 218
                  :|.:   .||:.:  .||.|.:..|...|                |.|.:   |.||.:
Yeast   229 NLSEIPVPQKTLASRFLTIAESEPFGPVDAAHVLE----------------LEPAV---ETLRNL 274

Human   219 YSQDRH 224
            .:...|
Yeast   275 STVGEH 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRPS22	NP_064576.1	MRP-S22	70..309	CDD:431167	40/194 (21%)
MRPS35	NP_011681.1	Bot1p	133..303	CDD:403498	36/169 (21%)