Protein Alignment NMUR2 and Nmur2

DIOPT Version :10

• Sequence 1: NP_064552.3
• Gene: NMUR2 / 56923
• HGNCID: 16454
• Length: 415
• Species: Homo sapiens
• Sequence 2: NP_071611.3
• Gene: Nmur2 / 64042
• RGDID: 621155
• Length: 395
• Species: Rattus norvegicus
• Alignment Length: 393
• Identity: 311/393 - (79%)
• Similarity: 347/393 - (88%)
• Gaps: 5/393 - (1%)

Human     4 MEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCL 68
            |.||:|||||:     ||..|:|||||||||.||||:||...|||||.|..||:|||:||:|||:
  Rat     1 MGKLENASWIH-----DPLMKYLNSTEEYLAHLCGPKRSDLSLPVSVAYALIFLVGVMGNLLVCM 60

Human    69 VILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFAS 133
            ||::||.:||||||||||||||||||||||||||:||||.|||||||||||||||||||||||||
  Rat    61 VIVRHQTLKTPTNYYLFSLAVSDLLVLLLGMPLEIYEMWHNYPFLFGPVGCYFKTALFETVCFAS 125

Human   134 ILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLV 198
            |||:|||||||||||:|||||||:||||||||||.:||.|||:|||||||||||||.:|||||.|
  Rat   126 ILSVTTVSVERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQHFPNGSSV 190

Human   199 PGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCR 263
            ||||||||.||||:||.|||.||||||:||||:||||||||.||||:|:||||::...||.||.|
  Rat   191 PGSATCTVTKPMWVYNLIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEANKVAVNIHRPSR 255

Human   264 KSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYN 328
            |||.||||||||||||||.|||:|||||||||||:|||||||||:||||||||||||||||||||
  Rat   256 KSVTKMLFVLVLVFAICWTPFHVDRLFFSFVEEWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYN 320

Human   329 LLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHNSHL 393
            ||||||:|||:||:|...|..|.:|.||.||||:.|||||||.||||||.|||||.|||:||::|
  Rat   321 LLSRRFRAAFRNVVSPTCKWCHPRHRPQGPPAQKIIFLTECHLVELTEDAGPQFPGQSSIHNTNL 385

Human   394 PAA 396
            ..|
  Rat   386 TTA 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NMUR2	NP_064552.3	7tmA_NMU-R2	46..338	CDD:320479	246/291 (85%)
		TM helix 1	46..73	CDD:320479	18/26 (69%)
		TM helix 2	80..106	CDD:320479	24/25 (96%)
		TM helix 3	119..149	CDD:320479	28/29 (97%)
		TM helix 4	161..183	CDD:320479	17/21 (81%)
		TM helix 5	213..242	CDD:320479	23/28 (82%)
		TM helix 6	261..291	CDD:320479	25/29 (86%)
		TM helix 7	306..331	CDD:320479	23/24 (96%)
		NmU-R2_C_term	331..397	CDD:466027	44/66 (67%)
Nmur2	NP_071611.3	7tm_GPCRs	38..330	CDD:475119	246/291 (85%)
		TM helix 1	40..64	CDD:410628	16/23 (70%)
		TM helix 2	73..95	CDD:410628	21/21 (100%)
		TM helix 3	112..134	CDD:410628	20/21 (95%)
		TM helix 4	157..173	CDD:410628	11/15 (73%)
		TM helix 5	206..229	CDD:410628	18/22 (82%)
		TM helix 6	259..281	CDD:410628	18/21 (86%)
		TM helix 7	298..323	CDD:410628	23/24 (96%)
		NmU-R2_C_term	323..389	CDD:466027	44/66 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..395		9/15 (60%)