Protein Alignment NMUR2 and nmur1a

DIOPT Version :10

• Sequence 1: NP_064552.3
• Gene: NMUR2 / 56923
• HGNCID: 16454
• Length: 415
• Species: Homo sapiens
• Sequence 2: XP_021325138.1
• Gene: nmur1a / 557276
• ZFINID: ZDB-GENE-081104-220
• Length: 428
• Species: Danio rerio
• Alignment Length: 384
• Identity: 193/384 - (50%)
• Similarity: 256/384 - (66%)
• Gaps: 37/384 - (9%)

Human    26 LNSTE-----------EYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTP 79
            ||.||           |||....|||||..||||.:.|:.||:||.:||:|.|:||.:::.|:||
Zfish    29 LNLTEMEIEDFCLDQDEYLEKYLGPRRSPVFLPVCLTYLLIFLVGAVGNILTCIVIAKNKVMRTP 93

Human    80 TNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVER 144
            ||:||||||:|||||||||||||:||||.|||||.|..||||||.|||||||||||::|.:||||
Zfish    94 TNFYLFSLAISDLLVLLLGMPLELYEMWSNYPFLLGKGGCYFKTLLFETVCFASILNVTALSVER 158

Human   145 YVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNG---SLVPGSATCTV 206
            |:|::||.|||...||..|.|::..||..|||.::|||.:|||.....|.|   .::..||||.:
Zfish   159 YIAVIHPLRAKYVVTRTHAKRLILSVWSISVLCAIPNTILHGIFTLPPPKGKAAGVMLDSATCML 223

Human   207 IKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNA--------NI----Q 259
            :||.|:||.|||:|:.||:||||..|||||.|:.::||::|.|:..|..|        |:    |
Zfish   224 VKPRWMYNLIIQITTLLFFLLPMLTISVLYLLIGMQLKREKMLQVLEAKASSGLDSSSNVRSQQQ 288

Human   260 RPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSE---SLAAVFNLVHVVSGVFFYLSSA 321
            :..|:.|.|||||||::|.|||||||.|||.:||:::...   .:..|:..|||:||||||||||
Zfish   289 KTRRQQVTKMLFVLVVMFGICWAPFHTDRLMWSFMDQKDSEHIEIFEVYEYVHVISGVFFYLSSA 353

Human   322 VNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGP 380
            :||::|||:|.||:..|:.|:.  |.:|..      .|.:|::.:|.........|:.|
Zfish   354 INPVLYNLMSTRFREMFKEVMC--HHKWRP------VPRKRSLSMTRVTVRSTVSDVPP 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NMUR2	NP_064552.3	7tmA_NMU-R2	46..338	CDD:320479	171/309 (55%)
		TM helix 1	46..73	CDD:320479	14/26 (54%)
		TM helix 2	80..106	CDD:320479	22/25 (88%)
		TM helix 3	119..149	CDD:320479	23/29 (79%)
		TM helix 4	161..183	CDD:320479	9/21 (43%)
		TM helix 5	213..242	CDD:320479	18/28 (64%)
		TM helix 6	261..291	CDD:320479	20/29 (69%)
		TM helix 7	306..331	CDD:320479	18/24 (75%)
		NmU-R2_C_term	331..397	CDD:466027	12/50 (24%)
nmur1a	XP_021325138.1	7tmA_NMU-R1	60..370	CDD:320480	171/309 (55%)
		TM helix 1	60..87	CDD:320480	14/26 (54%)
		TM helix 2	94..120	CDD:320480	22/25 (88%)
		TM helix 3	133..163	CDD:320480	23/29 (79%)
		TM helix 4	175..197	CDD:320480	9/21 (43%)
		TM helix 5	230..259	CDD:320480	18/28 (64%)
		TM helix 6	290..320	CDD:320480	20/29 (69%)
		TM helix 7	338..363	CDD:320480	18/24 (75%)